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前列腺跨膜上皮3抗原抗體

英文名稱 STEAP3
中文名稱 前列腺跨膜上皮3抗原抗體
別    名 1010001D01Rik; Dudlin 2; Dudlin2; Dudulin 2; Dudulin-2; Dudulin2; hpHyde; hTSAP6; Metalloreductase STEAP3; MGC93147; pHyde; Six transmembrane epithelial antigen of prostate 3; Six transmembrane prostate protein 3; Six-transmembrane epithelial antigen of prostate 3; STEA 3; STEA3_HUMAN; STEAP 3; STEAP family member 3; STEAP family member 3 metalloreductase; STEAP3; STMP 3; STMP3; TSAP 6; TSAP6; Tumor suppressor activated pathway protein 6; Tumor suppressor
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STEAP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 Function:
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Subcellular Location:
Endosome membrane. Localizes to vesicular-like structures at the plasma membrane and around the nucleus.

Tissue Specificity:
Expressed in adult bone marrow, placenta, liver, skeletal muscle and pancreas. Down-regulated in hepatocellular carcinoma.

Post-translational modifications:xy-11105R    Ninjurin 1神經(jīng)損傷誘導(dǎo)蛋白1抗體
xy-11106R    Ninjurin 2神經(jīng)損傷誘導(dǎo)蛋白2抗體
xy-6261R    NEK3絲氨酸/蘇氨酸蛋白激酶Nek3抗體
xy-5732R    NEK2中心體相關(guān)蛋白激酶Nek2抗體
xy-11435R    Neurogranin神經(jīng)顆粒素抗體
xy-11428R    Neuropeptide S神經(jīng)肽S抗體
xy-11429R    Neuropeptide S神經(jīng)肽S抗體
xy-11430R    NPSR1神經(jīng)肽S受體1/G蛋白偶聯(lián)受體154抗體
xy-11420R    NMUR1G蛋白偶聯(lián)受體66/神經(jīng)調(diào)節(jié)肽U受體1抗體
xy-11421R    NMUR2G蛋白偶聯(lián)受體FM4/神經(jīng)調(diào)節(jié)肽U受體2抗體
xy-11422R    Neuropeptide S神經(jīng)肽S抗體
xy-11409R    NR0B1腎上腺發(fā)育不全相關(guān)蛋白抗體
xy-7627R    NS5ATP9丙型肝炎病毒非結(jié)構(gòu)蛋白5A反式激活蛋白9抗體
xy-7074R    NoxaNoxa蛋白抗體
xy-7073R    NME5P53誘導(dǎo)細(xì)胞凋亡抑制蛋白抗體
xy-5526R    phospho-TrkB (Tyr705)磷酸化酪氨酸激酶B抗體
xy-5523R    phospho-NDEL1(Ser242)磷酸化中心粒蛋白Nudel抗體
xy-5524R    phospho-NDEL1(Thr219)磷酸化中心粒蛋白Nudel抗體
xy-3961R    NDUFS4線粒體復(fù)合物NDUFS4蛋白抗體
xy-3958R    NDUFA8NADH脫氫酶α家族8抗體
xy-3959R    NDUFV1NADH脫氫酶黃素蛋白1抗體
xy-3960R    NDUFV2NADH脫氫酶黃素蛋白2抗體
xy-3956R    NDUFA1NADH氧化還原酶輔酶1抗體
xy-8511R    NOD26膜內(nèi)在蛋白NOD26抗體
xy-8566R    Phospho-NMDAR2B (Tyr1474)磷酸化谷氨酸受體2B抗體
xy-8567R    Phospho-NMDAR2A + 2B (Tyr1246 + Tyr1252)磷酸化谷氨酸受體2A+2B抗體
xy-5271R    NEK6高度相似的細(xì)胞周期蛋白激酶NEK6抗體
xy-4839R    nonstructural protein 1A型流感病毒-NS1抗體（神經(jīng)氨酸酶1）
xy-10186R    NET1去甲腎上腺素轉(zhuǎn)運(yùn)蛋白/神經(jīng)遞質(zhì)去甲腎上腺素轉(zhuǎn)運(yùn)體抗體
xy-13071R    Phospho-eNOS (Ser1176)磷酸化一氧化氮合成酶3（內(nèi)皮型）抗體
xy-3552R    Nesfatin-1新的飽食分子蛋白抗體