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STOX1蛋白抗體

英文名稱 STOX1
中文名稱 STOX1蛋白抗體
別    名 C10orf24; chromosome 10 open reading frame 241; PEE4; storkhead box 1; Storkhead-box protein 1; STOX1; STOX1_HUMAN; Winged-helix domain-containing protein.
  
說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 111kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STOX1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Subcellular Location:
Nucleus; Nucleus > nucleolus and Cytoplasm. Nucleus. Either found in the cytoplasm or in the nucleus. Nuclear expression of isoform A seems to be restricted to polyploid trophoblast cells.

DISEASE:
Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4) [MIM:609404]; also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta.

Database links:

Entrez Gene: 219736 Human

Omim: 609397 Human

SwissProt: Q6ZVD7 Human

Unigene: 37636 Humanxy-1495R    OCLN緊密連接蛋白抗體
xy-7001R    OCIAD1卵巢癌免疫反應(yīng)抗原抗體
xy-2699R    OMPC大腸桿菌外膜孔道蛋白C抗體
xy-2693R    Plexin B1神經(jīng)叢蛋白B1抗體
xy-5560R    phospho-PRKCZ(Thr410)磷酸化蛋白激酶C(T410)抗體
xy-5561R    phospho-PRKD1(Ser738)磷酸化蛋白激酶C mu型抗體
xy-5563R    phospho-PRKD1(Tyr463)磷酸化蛋白激酶C mu型抗體
xy-2690R    PILR beta細胞表面受體PILRβ抗體
xy-7002R    PAGE4前列腺癌相關(guān)蛋白4抗體
xy-7003R    PMPCB線粒體導(dǎo)肽水解酶β抗體
xy-9408R    PRR15富含脯氨酸蛋白15抗體
xy-10486R    protein C light chain維生素K依賴的蛋白C輕鏈抗體
xy-10487R    protein C Activation peptide
xy-0686R    PTEN一種腫瘤抑制基因抗體（C端）
xy-1478R    PAFR血小板活化因子受體抗體
xy-5422R    PP1C gamma蛋白磷酸酶γ1抗體
xy-4181R    p53R2核苷酸還原酶M2B抗體
xy-2384R    PDE4A磷酸二酯酶4A抗體
xy-3643R    PLASTIN3絲束蛋白T Plastin抗體
xy-3638R    Plexin A2神經(jīng)叢蛋白A2抗體
xy-3640R    Plectin網(wǎng)蛋白抗體
xy-10171R    PTOV1前列腺腫瘤高表達蛋白1抗體
xy-5596R    phospho-P53(Thr55)磷酸化腫瘤抑制基因P53抗體
xy-4180R    P2Y2嘌呤ATP受體抗體
xy-2210R    phospho-p38 MAPK (Thr180 + Tyr182)磷酸化絲裂原活化蛋白激酶p38抗體
xy-2219R    Pectinesterase inhibitor 18果膠酶抑制蛋白18抗體
xy-3614R    PPAR alphaα型-過氧化酶活化增生受體抗體（PPAR α, PPAR-α）
xy-2561R    PSGD/HOXB13同源盒蛋白HOXB13抗體
xy-5537R    Phospho-PDPK1(Ser393)磷酸化3磷酸肌醇依賴性蛋白激酶1抗體
xy-3716R    Phospho-p63 (Ser160+Ser162)磷酸化P63腫瘤抑制基因抗體
xy-2270R    Phospho-PAK4(Ser99)磷酸化p21激活激酶4抗體
xy-3717R    Phospho-p73(Tyr99)磷酸化P73腫瘤抑制基因抗體
xy-3718R    Phospho-p95 NBS1 (Ser343)磷酸化DNA修復(fù)蛋白NBS1抗體
xy-1573R    PUMAp53正向細胞凋亡調(diào)控因子抗體