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溶質(zhì)載體蛋白家族47成員A1抗體

英文名稱 SLC47A1
中文名稱 溶質(zhì)載體蛋白家族47成員A1抗體
別    名 1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.
 
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC47A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

Function:
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

Subcellular Location:
Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.

Tissue Specificity:
Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).

Similarity:
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

Database links:

Entrez Gene: 55244 Human

Omim: 609832 Human

SwissProt: Q96FL8 Human

Unigene: 232054 Humanxy-9505R    alpha 2 Macroglobulinα2巨球蛋白(α-2M)抗體
xy-9062R    ACCSLACCSL蛋白抗體
xy-4708R    AFP甲胎蛋白抗體
xy-11058R    Mint3β淀粉樣前體蛋白結(jié)合蛋白3抗體
xy-11072R    ASTN2星形肌動(dòng)蛋白抗體
xy-11223R    TREX1系統(tǒng)性紅斑狼瘡相關(guān)蛋白TREX1抗體
xy-11224R    phospho-ATRIP (Ser68+Ser72)磷酸化系統(tǒng)性紅斑狼瘡先關(guān)蛋白TREX1抗體
xy-11225R    Phospho-ATRIP (Ser224)磷酸化系統(tǒng)性紅斑狼瘡相關(guān)蛋白TREX1抗體
xy-11241R    AP2M1接頭相關(guān)蛋白復(fù)合體AP-2μ鏈1抗體
xy-11242R    Phospho-AP2M1 (Thr156)磷酸化接頭相關(guān)蛋白復(fù)合體AP-2μ鏈1抗體
xy-4901R    Annexin A7膜粘連蛋白7抗體
xy-9823R    C3orf153號(hào)染色體開放閱讀框15抗體
xy-6336R    APOB48R載脂蛋白B受體抗體
xy-6332R    ABCA2三磷酸腺苷結(jié)合盒轉(zhuǎn)運(yùn)蛋白2抗體
xy-6333R    ApoB 載脂蛋白B抗體
xy-6335R    ALOX15B花生四烯酸15脂氧合酶2抗體
xy-6338R    APOC4載脂蛋白C4抗體
xy-6337R    ARH低密度脂蛋白受體銜接蛋白抗體
xy-7550R    AUP1原始廣泛存在蛋白1抗體
xy-9398R    ANKRD37錨蛋白重復(fù)結(jié)構(gòu)域蛋白37抗體
xy-7588R    A4GALTα1,4-半乳糖基轉(zhuǎn)移酶1
xy-7642R    AGTRAP血管緊張素Ⅱ受體相關(guān)蛋白抗體
xy-7669R    AX2R膜粘連蛋白2受體抗體
xy-0203R    ACEI血管緊張素1轉(zhuǎn)換酶抑制劑抗體
xy-1229R    AATF拮抗凋亡轉(zhuǎn)錄因子抗體
xy-0094R    AACT-Alpha1α-1抗胰糜蛋白酶抗體
xy-0096R    alpha 1 Antitrypsinα-1抗胰蛋白酶抗體
xy-1224R    ABCB6ATP結(jié)合蛋白家族6抗體
xy-1231R    ABCG1三磷酸腺苷結(jié)合盒亞家族G1抗體
xy-0611R    Adiponectin receptor 2脂聯(lián)素受體2抗體
xy-9741R    ANGEL1ANGEL1蛋白抗體
xy-9742R    ANGEL2ANGEL2蛋白抗體
xy-9743R    ANKLE2ANKLE2蛋白抗體
xy-9744R    ANKMY1睪丸特異性錨樣蛋白1抗體
xy-9745R    ANKRD13B錨蛋白重復(fù)結(jié)構(gòu)域蛋白13B抗體
xy-9746R    ANKRD20A1錨蛋白重復(fù)結(jié)構(gòu)域蛋白20A1抗體
xy-9747R    ANKRD20A3錨蛋白重復(fù)結(jié)構(gòu)域蛋白20A3抗體
xy-9748R    ANKRD22錨蛋白重復(fù)結(jié)構(gòu)域蛋白22抗體