小核RNA激活復(fù)合多肽SNAPC5抗體 返回列表頁

小核RNA激活復(fù)合多肽SNAPC5抗體

英文名稱 SNAPC5
中文名稱 小核RNA激活復(fù)合多肽SNAPC5抗體
別    名 Small nuclear RNA activating complex polypeptide 5 19kDa; Small nuclear RNA activating complex polypeptide 5; SNAP 19; SNAP19; SNAPc 19 kDa subunit; SNAPC 5; SNAPc subunit 5; snRNA activating protein complex 19 kDa subunit; snRNA activating protein complex subunit 5.
   
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Rabbit, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNAPC5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SNAPC5 is a subunit of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC5 binds to the proximal sequence element (PSE) common to the promotor regions of these 2 types of genes, and recruits TBP and BRF2 to the U6 snRNA TATA box.

Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

Subunit:
Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC5 interacts with SNAPC4.1 Publication.

Subcellular Location:
Nuclear.

Database links:

Entrez Gene: 10302 Human

Entrez Gene: 330959 Mouse

Entrez Gene: 691501 Rat

Omim: 605979 Human

SwissProt: O75971 Human

SwissProt: Q8R2K7 Mouse

Unigene: 30174 Human

Important Note:
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