蔗糖非發(fā)酵蛋白SNF2H抗體 返回列表頁

蔗糖非發(fā)酵蛋白SNF2H抗體

英文名稱 SNF2H
中文名稱 蔗糖非發(fā)酵蛋白SNF2H抗體
別    名 4933427E24Rik; ATP-dependent chromatin remodeling protein SNF2H; D030040M08Rik; D330027N15Rik; EC 3.6.1.-; hISWI; hSNF2H; ISWI; MommeD4; SMARCA5; SMCA5; SMCA5_HUMAN; Snf2h; Sucrose nonfermenting like 5; Sucrose nonfermenting protein 2 homolog; Sucrose nonfermenting, yeast, homolog of; sucrose nonfermenting-like 5; SWI/SNF related matrix associated actin dependent regulator of chromatin a5; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 5; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; WCRF135.
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 122kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNF2H
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]

Function:
Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.

Subcellular Location:
Nucleus.xy-2433R    ATP4B氫鉀ATP酶通道蛋白抗體
xy-2435R    ATP5AATP5A抗體
xy-0385R    Arg3.1即刻早期基因ARC抗體
xy-1145R    ARF6ADP核糖基化因子6抗體
xy-0114M    Aromatase芳香化酶抗體
xy-0055R    ArteminArtemin抗體
xy-0600R    ADRA1Aalpha 1腎上腺素能受體A抗體
xy-0630R    Angiotensin II Type 1 Receptor血管緊張素Ⅱ-1型受體抗體
xy-0519R    ATF3活化轉(zhuǎn)錄因子3抗體
xy-2430R    APJ Receptor血管緊縮素樣蛋白1抗體
xy-2432R    APG7自噬相關(guān)蛋白7抗體
xy-11071R    ANTXR2炭疽毒素受體2抗體
xy-4008R    ATG4C自噬相關(guān)蛋白4C抗體
xy-4005R    APG5L自噬蛋白5/細(xì)胞凋亡的特異性蛋白抗體
xy-4006R    ARSA芳基硫酸酯酶A抗體
xy-2249R    ACA11擬南芥ACA11抗體
xy-2247R    AHA3AHA3抗體（擬南芥）
xy-3064R    Phospho-ATP1A1 (Ser23)磷酸化鈉鉀ATP酶蛋白a1抗體
xy-5436R    phospho-ASK1 (Ser83)磷酸化細(xì)胞凋亡信號調(diào)節(jié)激酶1抗體
xy-5162R    AADACL1中性膽固醇酯水解酶1抗體
xy-1612R    Astrocyte人星形膠質(zhì)細(xì)胞抗體
xy-2406R    Aldolase A醛縮酶A抗體
xy-1471R    Annexin VI膜粘連蛋白6抗體
xy-0872R    beta-Amyloid(25-35)β淀粉樣肽（25-35）抗體
xy-1707R    Angiotensin I血管緊張素I抗體
xy-0995R    Adrenomedullin腎上腺髓質(zhì)素抗體(N端20肽)
xy-1442R    Arfaptin 2ADP核糖基化因子結(jié)合蛋白2抗體
xy-1705R    AVPR2精氨酸加壓素受體2抗體
xy-6741R    ASC凋亡相關(guān)斑點(diǎn)樣蛋白ASC抗體
xy-2754R    Afadin絲狀肌動蛋白結(jié)合蛋白抗體
xy-1636R    Antithrombin III 抗凝血酶3抗體
xym-0945M    Serum albumin (3F4)人血清白蛋白單克隆抗體
xy-2688R    ApoA4載脂蛋白A4抗體
xy-2201R    phospho-GEF H1 (Ser886)磷酸化Rho鳥苷酸交換因子2抗體
xy-3072R    phospho-Afadin (Ser1721)磷酸化絲狀肌動蛋白結(jié)合蛋白抗體
xy-12526R    ARPC1A肌動蛋白相關(guān)蛋白2/3亞型1A抗體
xy-9749R    ANKRD32錨蛋白重復(fù)結(jié)構(gòu)域蛋白32抗體
xy-9754R    ATXN7L3B共濟(jì)失調(diào)7樣蛋白3B抗體
xy-9107R    POP1感染性蛋白*蛋白1抗體