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SNRNP200蛋白抗體

英文名稱 SNRNP200
中文名稱 SNRNP200蛋白抗體
別    名 Activating signal cointegrator 1 complex subunit 3 like 1; ASCC3L1; BRR2; BRR2 homolog; HELIC2; RP33; SNRNP200; U5 200KD; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP specific 200 kDa protein.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 244kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNRNP200
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximay 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]

Function:
Putative RNA helicase involved in the second step of RNA splicing. May promote one or more conformational changes in the dynamic network of RNA-RNA interactions in the spliceosome. Appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices.

Subcellular Location:
Nucleus.

Tissue Specificity:
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xy-1103R    CD274程序性死亡配體1抗體
xy-0673R    B7H4B7-H4抗體
xy-0164R    BACE1β分泌酶抗體
xy-0892R    Bad相關(guān)死亡促進(jìn)因子Bad抗體
xy-0127M    BaxBax
xy-1868R    B7-DC程序性死亡配體2抗體
xy-1954R    BSEP膽汁酸鹽輸出泵/ATP結(jié)合盒轉(zhuǎn)運(yùn)蛋白11抗體
xym-0390M    Beta-2-MG(B2E5)β2微球蛋白抗體(單抗)
xy-7552R    Biglycan骨/軟骨蛋白多糖1抗體
xy-9759R    CAP染色體相關(guān)蛋白CAP抗體
xy-9269R    BECN1L1Bcl-2同源結(jié)構(gòu)域樣蛋白1抗體
xy-7657R    BAG6Bcl2相關(guān)抗凋亡基因6抗體
xy-9728R    B4GALT7半乳糖轉(zhuǎn)移酶7亞基β1,4抗體
xy-9270R    BEND5BEN結(jié)構(gòu)域蛋白5抗體
xy-9438R    BBS5巴德-畢德氏綜合征蛋白BBS5抗體
xy-9727R    BIN2乳腺癌相關(guān)蛋白1抗體
xy-9492R    Brain protein CG6腦蛋白CG6抗體
xy-11015R    BFSP2晶狀體蛋白2抗體
xy-9542R    C7orf277號染色體開放閱讀框27抗體
xy-8211R    BCMP101乳腺癌膜相關(guān)蛋白101抗體
xy-4542R    BRLF1立即早期癌基因BRLF1抗體（鼻咽癌基因）
xy-4989R    BDNF腦源神經(jīng)營養(yǎng)因子抗體
xy-11680R    BACE2β淀粉樣前體蛋白裂解酶2抗體
xy-11808R    BHLHB5螺旋一環(huán)一螺旋蛋白5抗體
xy-11809R    BPNT1二磷酸3核苷酸酶抗體
xy-11810R    BRSK2腦蛋白絲氨酸/蘇氨酸激酶29抗體
xy-11811R    BRWD3智力發(fā)育調(diào)節(jié)相關(guān)蛋白BRWD3抗體
xy-11813R    BTD生物素酶抗體
xy-7097R    BifBax相互作用因子1抗體
xy-6882R    BRF2表皮生長因子反應(yīng)蛋白2抗體
xy-7079R    Bax betaBCL2相關(guān)X蛋白抗體
xy-7584R    Bcl 2 like 13 proteinBcl2樣凋亡蛋白13抗體
xy-7585R    BCL2 like 14Bcl2樣凋亡蛋白14抗體
xy-7587R    Bcl2 modifying factorBcl2蛋白修飾因子抗體
xy-7076R    BMP11骨形態(tài)發(fā)生蛋白11抗體
xy-7582R    BCL2L15BCL2樣15促凋亡蛋白抗體
xy-6292R    Bone Alkaline Phosphatase骨堿性磷酸酶抗體
xy-9687R    Phospho-BLNK(Tyr84)磷酸化T淋巴細(xì)胞連接蛋白抗體