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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> SWI/SNF相關(guān)基質(zhì)關(guān)聯(lián)肌動蛋白依賴染色質(zhì)調(diào)控因子亞家族D2抗體

SWI/SNF相關(guān)基質(zhì)關(guān)聯(lián)肌動蛋白依賴染色質(zhì)調(diào)控因子亞家族D2抗體

參   考   價(jià): 17

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

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所  在  地上海

更新時(shí)間:2015-06-11 09:24:56瀏覽次數(shù):444次

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SWI/SNF相關(guān)基質(zhì)關(guān)聯(lián)肌動蛋白依賴染色質(zhì)調(diào)控因子亞家族D2抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.

SWI/SNF相關(guān)基質(zhì)關(guān)聯(lián)肌動蛋白依賴染色質(zhì)調(diào)控因子亞家族D2抗體

英文名稱 SMARCD2
中文名稱 SWI/SNF相關(guān)基質(zhì)關(guān)聯(lián)肌動蛋白依賴染色質(zhì)調(diào)控因子亞家族D2抗體
別    名 60 kDa BRG 1/Brm associated factor subunit B; 60 kDa BRG1/Brm associated factor subunit B; BAF60B; BRG1 associated factor 60B; Chromatin remodeling complex BAF60B subunit; CRACD 2; CRACD2; Mammalian chromatin remodeling complex BRG1 associated factor 60B; PRO2451; Rsc6p; SMARCD 2; SWI/SNF complex 60 kDa subunit B; SWI/SNF related matrix associated actin dependent regulator of chromatin d2; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 2; Swp73 like protein.
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SMARCD2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).

Subunit:
Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. May interact with SMARCA4, the catalytic subunit of the SWI/SNF related nucleosome-remodeling complexes BRG1(I) and BRG1(II). The precise distribution of the related SMARCD1, SMARCD2 and SMARCD3 proteins among these and other SWI/SNF nucleosome-remodeling complexes is not fully known. Interacts with UNKL.
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