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磷酸化基底膜相關(guān)軟骨素蛋白多糖抗體

英文名稱(chēng) phospho-SMC3 (Ser1083)
中文名稱(chēng) 磷酸化基底膜相關(guān)軟骨素蛋白多糖抗體
別    名 SMC3 (phospho S1083); p-SMC3 (phospho S1083); CDLS2; DKFZp686L19178; DXhXs423e; DXS423E; KIAA0178; MGC138332; OTTHUMP00000061876; RP6 29D12.1; SB1.8; Segregation of mitotic chromosomes 1; Segregation of mitotic chromosomes like 1; SMC 1; SMC protein 1B; SMC-1-beta; SMC-1B; SMC1; SMC1A; SMC1alpha; SMC1alpha protein; SMC1B; SMC1B_HUMAN; SMC1BETA; SMC1beta protein; SMC1L1; SMC1L2; SMCB; Structural maintenance of chromosome 1 like 1 protein; Structural maintenance of chromosome 1 like 2 protein; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes 1B; Structural maintenance of chromosomes protein 1B.
    
說(shuō) 明 書(shū) 0.1ml  
產(chǎn)品類(lèi)型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 141kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human SMC3 around the phosphorylation site of Ser1083.
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]

Function:
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.xy-6757R    BCA2乳腺癌相關(guān)基因2抗體（鋅指蛋白364）
xy-6646R    BLKB淋巴細(xì)胞酪氨酸激酶抗體
xy-7514R    BAI2腦特異性血管生成抑制蛋白2抗體
xy-5798R    BNIP3L促凋亡BNIP3L蛋白抗體
xy-5799R    BAG3Bcl2抑凋亡蛋白Bag3抗體
xy-5796R    BCL2L10BCL2樣10促凋亡蛋白抗體
xy-5797R    BCL2L12BCL2樣12含脯氨酸蛋白抗體
xy-5800R    BAG5BCL2分子伴侶調(diào)節(jié)蛋白5抗體
xy-12900R    BTF3轉(zhuǎn)錄因子BTF3抗體
xy-6682R    BNIP2Bcl2相互作用蛋白2抗體
xy-5928R    BASC4乳腺癌擴(kuò)增序列蛋白4抗體
xy-6258R    Phospho-Bcr (Tyr360)磷酸化T淋巴細(xì)胞受體抗體
xy-9292R    BNC1堿性核蛋白1/鋅指蛋白basonuclin抗體
xy-6508R    BCMP11乳腺癌膜蛋白11抗體（前梯度同源蛋白2）
xym-4579M    BNP(H1G3)人腦鈉素單克隆抗體
xy-3850R    BCMAB淋巴細(xì)胞成熟因子抗體
xy-3784R    Bik促凋亡Bik蛋白抗體
xy-5994R    BCSC1乳腺癌抑癌蛋白抗體
xy-4291R    BARD1乳腺癌易感基因環(huán)狀結(jié)構(gòu)域蛋白抗體
xy-5992R    BRCAA1乳腺癌相關(guān)抗原BRCAA1抗體
xy-5993R    Bex1腦組織表達(dá)X連鎖蛋白1抗體
xy-2748R    BLNKB淋巴細(xì)胞連接蛋白抗體
xy-3054R    Phospho-BLNK (Tyr96)磷酸化T淋巴細(xì)胞連接蛋白抗體
xy-2747R    BcrBcr抗體
xy-3051R    Phospho-BAP1 (Ser592)磷酸化乳腺癌易感基因1抗體
xy-3052R    Phospho-Bcl-2 (Ser70)磷酸化Bcl-2抗體
xy-3053R    Phospho-Bcl-2 (Thr56)磷酸化Bcl-2抗體
xy-3067R    Phospho-Bcr (Tyr177)磷酸化T淋巴細(xì)胞受體抗體
xy-7739R    BIN3細(xì)胞骨架銜接蛋白BIN3抗體
xy-6900R    BOD1雙向染色體細(xì)胞分裂蛋白1抗體
xy-3669R    BRN3A轉(zhuǎn)錄因子Brn3蛋白抗體Brn3α
xy-3671R    BMP6骨形態(tài)發(fā)生蛋白6抗體
xy-2207R    BNP腦鈉素抗體
xy-3663R    BMP3骨形態(tài)發(fā)生蛋白3抗體
xy-3664R    Bag1抑凋亡基因bag1抗體
xy-3668R    Brs3蛙皮素受體3抗體
xy-3670R    BMP8骨形態(tài)發(fā)生蛋白8抗體
xy-10090R    BMP6骨形態(tài)發(fā)生蛋白6抗體
xy-12577R    Phospho-Bcl2 (Ser87)磷酸化Bcl-2抗體
xy-12578R    Phospho-Bcl2 (Thr69)磷酸化Bcl-2抗體
xy-12579R    phospho-Bcl-xL (Thr47)磷酸化Bcl-xL蛋白抗體