溶質(zhì)載體家族蛋白9成員3調(diào)節(jié)因子2抗體 返回列表頁

溶質(zhì)載體家族蛋白9成員3調(diào)節(jié)因子2抗體

英文名稱 SLC9A3R2
中文名稱 溶質(zhì)載體家族蛋白9成員3調(diào)節(jié)因子2抗體
別    名 E3KARP; HGNC:11076; Isoform 3 regulator 2; Isoform 3 regulatory factor 2; MGC104639; Na(+)/H(+) exchange regulatory cofactor NHE RF2; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHE3 kinase A regulatory protein; NHE3 kinase A regulatory protein E3KARP; NHE3 regulatory factor 2; NHE3RF2; NHERF 2; NHERF-2; NHERF2; NHRF2_HUMAN; OCTS2; SIP 1; SIP-1; SIP1; Slc9a3r2; Sodium hydrogen exchanger regulatory factor 2; Sodium-hydrogen exchanger regulatory factor 2; Sodium/hydrogen exchanger; Sodium/hydrogen exchanger regulatory factor 2; Solute carrier family 9 (sodium/hydrogen exchanger); Solute carrier family 9 (sodium/hydrogen exchanger) isoform 3 regulator 2; Solute carrier family 9 (sodium/hydrogen exchanger) isoform 3 regulatory factor 2; Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 2; Solute carrier family 9 isoform 3 regulator 2; Solute carrier family 9 isoform A3 regulatory factor 2; SRY interacting protein 1; SRY-interacting protein 1; TKA 1; TKA-1; TKA1; Tyrosine kinase activator protein 1.

說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC9A3R2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Function:
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.

Subcellular Location:
Endomembrane system. Nucleus. Apical cell membrane. Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern.xy-9545R    C9orf869號染色體開放閱讀框86抗體
xy-9976R    C21orf12821號染色體開放閱讀框128抗體
xy-9499R    C6orf626號染色體開放閱讀框62抗體
xy-9543R    CCZ1CCZ1蛋白抗體
xy-9553R    Cerebral protein 5腦蛋白5抗體
xy-9978R    C21orf5821號染色體開放閱讀框58抗體
xy-9700R    C20orf4320號染色體開放閱讀框43抗體
xy-9493R    C9ORF439號染色體開放閱讀框43抗體
xy-13905R    Chitinase 3 like protein 3幾丁質(zhì)酶3樣蛋白3抗體
xy-0263R    CMTM2趨化素樣因子超家族成員2抗體
xy-0265R    CKLFSF2 isoform 1趨化素樣因子超家族成員2亞型1抗體
xy-9652R    C18orf118號染色體開放閱讀框1抗體
xy-0264R    COX7A2細(xì)胞色素c氧化酶VIIA亞型2抗體
xy-11245R    CACNA1F鈣離子通道a1F亞型抗體
xy-11246R    Calcineurin B鈣調(diào)磷酸酶B亞基B1抗體
xy-11247R    CaMKK1鈣調(diào)蛋白激酶激酶α抗體CaMKKα
xy-11239R    CREB3L3環(huán)腺苷酸應(yīng)答元件結(jié)合蛋白H抗體
xy-11226R    Phospho-CHEK1 (Ser296)磷酸化細(xì)胞周期檢測點(diǎn)激酶1抗體
xy-6798R    Calpain 12鈣激活蛋白酶12抗體
xy-15093R    C20orf13420號染色體開放閱讀框134抗體
xy-7546R    CD239B細(xì)胞粘附分子CD239抗體
xy-7547R    CPB2胰羧肽酶B2抗體
xy-6873R    CERKL視網(wǎng)膜色素變性蛋白26抗體
xy-6365R    CROT過氧化物酶體肉堿酰基轉(zhuǎn)移酶抗體
xy-9629R    C16orf716號染色體開放閱讀框7抗體
xy-9631R    C16orf5716號染色體開放閱讀框57抗體
xy-9829R    C3orf373號染色體開放閱讀框37抗體
xy-9831R    C3orf493號染色體開放閱讀框49抗體
xy-15059R    C1orf2201號染色體開放閱讀框220抗體
xy-12161R    Calcyphosine 1鈣磷蛋白1抗體
xy-12163R    Calcyphosine 2鈣磷蛋白2抗體
xy-12167R    phospho-CSEN (Ser63)磷酸化鉀通道相互作用蛋白3抗體
xy-9627R    C16orf6116號染色體開放閱讀框61抗體
xy-12092R    CNG3視錐感光細(xì)胞環(huán)磷酸鳥苷門控通道蛋白CNG3抗體