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垂體瘤轉(zhuǎn)化蛋白2抗體

英文名稱 Securin 2
中文名稱 垂體瘤轉(zhuǎn)化蛋白2抗體
別    名 Pituitary tumor transforming 2; Pituitary tumor transforming gene 2 protein; Pituitary tumor-transforming gene 2 protein; PTTG2; PTTG2_HUMAN; Securin-2.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Cat, Chimpanzee, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Securin 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
PTTG is overexpressed in Jurkat and is also detected in human thymus, testis and placenta. PTTG is mainly expressed in the cytoplasm and is also partially localized to the nucleus. Vertebrate PTTG regulates the separin Esp1, which promotes chromatid separation, to overcome the cohesive forces that hold sister chromatids together. This regulatory function of PTTG suggests that defective regulation of cohesion may contribute to cancer by promoting chromosome instability. Although vertebrate PTTG shares cell-cycle functions with its yeast securin counterparts Pds1p and Cut2, none share sequence homology

Subunit:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed at low levels in the pituitary, liver, spleen, prostate, testis, ovary, small intestine and colon. Also expressed in various pituitary, testicular, liver and ovarian tumors.

Similarity:
Belongs to the securin family.

Database links:

Entrez Gene: 10744 Human

Omim: 604231 Human

SwissProt: Q9NZH5 Human

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xy-0809R    Fibulin 1“衰老關(guān)鍵蛋白"抗體
xy-0895R    FSH receptor促卵泡刺激素受體抗體
xy-9760R    FGF12成纖維細(xì)胞生長(zhǎng)因子12抗體
xy-9761R    FGF14成纖維細(xì)胞生長(zhǎng)因子14抗體
xy-2135R    FABPB腦型脂肪酸結(jié)合蛋白抗體
xy-9729R    FAM96BFAM96B蛋白抗體
xy-9721R    FEZ1腦胚胎鋅指樣蛋白1抗體
xy-9723R    FAM29AFAM29蛋白抗體
xy-9738R    FASP1MaFF相關(guān)蛋白抗體
xy-4846R    Factor VII凝血因子7抗體
xy-7113R    FEM 1BFEM1B抗體
xy-1255R    FGF3纖維母細(xì)胞生長(zhǎng)因子3抗體
xy-1256R    FGF4纖維母細(xì)胞生長(zhǎng)因子4抗體
xy-1154R    FRA1FRA-1蛋白抗體
xy-12264R    FTSJ1精神發(fā)育遲滯相關(guān)蛋白抗體
xy-12165R    FAM62C延伸突觸蛋白3抗體
xy-12166R    Fibrillin 2原纖維蛋白2抗體
xy-7662R    FLI1尤文肉瘤FLI1蛋白抗體
xy-7636R    FUT1巖藻糖轉(zhuǎn)移酶1抗體
xy-6766R    FLIP delta + gamma凋亡調(diào)節(jié)蛋白δ+γ抗體
xy-7068R    FOXO1 + FOXO3 + FOXO4叉頭蛋白O1/O3/O4抗體
xy-9730R    FAM82B微管相關(guān)蛋白FAM82B抗體
xy-7548R    Fibrinogen alpha chain纖維蛋白原A鏈抗體
xy-7061R    FAIM1FAS凋亡抑制分子1抗體
xy-6831R    FAIM2FAS凋亡抑制分子2
xy-11254R    Flotillin 2表皮細(xì)胞表面抗原1抗體
xy-9500R    Factor IX凝血因子9抗體
xy-9501R    Factor X凝血因子10抗體
xy-9502R    Factor XI light chain凝血因子11輕鏈抗體
xy-9503R    Factor XII heavy chain凝血因子12重鏈抗體