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小核核糖核蛋白E抗體

英文名稱(chēng) SNRPE
中文名稱(chēng) 小核核糖核蛋白E抗體
別    名 AL022645; B-raf; C76690; HYPT11; RUXE_HUMAN; Sm protein E; Sm-E; Small nuclear ribonucleoprotein E; SME; snRNP-E; snRNPE; snrpe.
  
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Chicken, Pig, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 10kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNRPE
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 Function:
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. 

Subunit:
U1 snRNP is for instance composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Component of the heptameric ring U7 snRNP complex, or U7 Sm protein core complex, at least composed of LSM10, LSM11, SNRPB, SNRPD3, SNRPE, SNRPF, SNRPG and U7 snRNA. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.

Subcellular Location:
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.xy-5366R    phospho-GNA12(Ser68)磷酸化鳥(niǎo)苷酸調(diào)節(jié)蛋白12抗體
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xy-4149R    GOLPH2高爾基體膜蛋白GP73抗體
xy-6151R    GPR172BG蛋白偶聯(lián)受體172B抗體
xy-6536R    GCET2生發(fā)中心B淋巴細(xì)胞相關(guān)蛋白2抗體
xy-6149R    GNAT3G蛋白轉(zhuǎn)錄因子α3抗體
xy-6150R    GPR124G蛋白偶聯(lián)受體124抗體（腫瘤血管內(nèi)皮標(biāo)記物）
xy-6594R    Galectin 1半乳糖凝集素1抗體
xy-6720R    GANABα葡萄糖苷酶2抗體
xy-5809R    Galectin 7半乳糖凝集素7抗體
xy-5886R    GCDFP15特異性囊腫病液體蛋白15抗體
xy-5932R    GCET1B淋巴細(xì)胞生發(fā)中心相關(guān)蛋白抗體
xy-5934R    GASC1鱗狀細(xì)胞癌增強(qiáng)蛋白1抗體
xy-9574R    G alpha gustGα gust抗體
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xy-7019R    GBP5G蛋白結(jié)合蛋白5抗體
xy-6813R    Cancer/testis antigen family 4 member 7腫瘤/睪丸抗原家族4亞型7抗體
xy-11501R    GFR alpha 3GDNF家族受體α3抗體 GFR α3
xy-11559R    GLRB甘氨酸受體β/GlyR β抗體
xy-11526R    GALP神經(jīng)甘丙肽樣肽GALP抗體
xy-11527R    GALR2甘丙肽受體2抗體
xy-11528R    GALR3甘丙肽受體3抗體
xy-11529R    Ghrelin Receptor腦腸肽受體抗體
xy-11659R    GRC5GRC5蛋白抗體
xy-11660R    Gbx1腸和大腦特定同源蛋白1抗體
xy-11843R    GDF6生長(zhǎng)分化因子6抗體
xy-11844R    GEFT鳥(niǎo)嘌呤核苷酸交換因子GEFT抗體
xy-11845R    GMF beta膠漿成熟因子β抗體
xy-11848R    GPR56蛋白偶聯(lián)受體56抗體
xy-11849R    Gbx2腸和大腦特定同源蛋白2抗體