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肌漿/內(nèi)質(zhì)網(wǎng)鈣ATP酶3抗體

英文名稱 SERCA3
中文名稱 肌漿/內(nèi)質(zhì)網(wǎng)鈣ATP酶3抗體
別    名 Adenosine triphosphatase calcium; AT2A3_HUMAN; Atp2a3; ATPase Ca(2+) transporting ubiquitous; ATPase Ca++ transporting ubiquitous; Calcium pump 3; Calcium translocating P type ATPase; Sarco/endoplasmic reticulum Ca2+ ATPase; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA 3; SERCA3; SERCA3b; SR Ca(2+) ATPase 3; SR Ca(2+)-ATPase 3.
 
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Chicken, Cow, Xenopus laevis, Xenopus tropicalis
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 114kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SERCA3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function:
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.

Subcellular Location:
Nucleus membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane.

Tissue Specificity:
Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues.

Similarity:
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.

Database links:xy-6879R    phospho-GATA4 (Ser262)磷酸化GATA結(jié)合蛋白4抗體
xy-1787R    GATA6GATA結(jié)合蛋白6抗體
xym-0933M    GLP-1(1G9)GLP-1單克隆抗體
xy-1351R    Granzyme B顆粒酶B抗體
xy-1380R    GPR30G蛋白偶聯(lián)受體30抗體
xy-9326R    GDAP2神經(jīng)節(jié)苷脂誘導(dǎo)分化相關(guān)蛋白2抗體
xy-0835R    GAPDH3-磷酸甘油醛脫氫酶
xy-0201R    GDNFRAGDNF家族受體α-1抗體
xy-1130R    Gemin 2運(yùn)動神經(jīng)元存活蛋白結(jié)合蛋白1抗體
xy-0472R    GLUT1葡萄糖轉(zhuǎn)運(yùn)蛋白1抗體
xy-0351R    GLUT2葡萄糖轉(zhuǎn)運(yùn)蛋白2抗體
xy-3168R    Phospho-Glucocorticoid Receptor (Ser211)磷酸化糖皮質(zhì)激素受體抗體
xy-15384R    GPR158 G蛋白偶聯(lián)受體GPR158蛋白抗體
xy-1720R    Gamma cateninγ連環(huán)蛋白/Catenin γ /γ鏈接素抗體
xy-4014R    GABARAPL2G1氨基丁酸A型受體相似蛋白2抗體
xy-2770R    Gab1接頭蛋白Gab 1抗體
xy-3161R    Phospho-GSK3 alpha (Ser21)磷酸化糖原合酶激酶3α抗體
xy-1641R    phospho-GAP43 (Ser41)磷酸化神經(jīng)生長相關(guān)蛋白43抗體
xy-0028R    GSK-3 Beta (CT)糖原合酶激酶-3β抗體
xy-2039R    GRGDS抗粘附多肽抗體
xy-6141R    GLIPR1腦膠質(zhì)瘤發(fā)病機(jī)制相關(guān)蛋白1抗體
xy-11735R    GPM6A神經(jīng)細(xì)胞膜糖蛋白M6a
xy-12020R    GPR101G蛋白偶聯(lián)受體101抗體
xy-1559R    GLP-1R胰高血糖素樣肽-1受體/GLP-1受體抗體
xy-10419R    GPI糖磷脂酰肌醇抗體
xy-10122R    phospho-gp130 (Ser782)磷酸化gp130抗體
xy-13442R    Glutathione Transferase zeta 1谷胱甘肽S轉(zhuǎn)移酶ζ1抗體
xy-13443R    GLYAT甘胺酸-N-?；D(zhuǎn)移酶抗體
xy-13444R    GLYATL1甘胺酸-N-?；D(zhuǎn)移酶樣1抗體
xy-13445R    G3PP 轉(zhuǎn)運(yùn)蛋白G3PP抗體
xy-13446R    Phospho-Glycogen synthase 1(Ser645)磷酸化葡萄糖合成酶1抗體
xy-13447R    Glycogenin 1糖原蛋白1
xy-13640R    GRAP生長因子受體結(jié)合蛋白2相關(guān)接頭蛋白抗體
xy-13641R    GRB 14生長因子受體結(jié)合蛋白14抗體
xy-13448R    GLYCTKHBeAg結(jié)合蛋白4/甘油激酶抗體
xy-13449R    GLYATL2甘胺酸-N-酰基轉(zhuǎn)移酶樣2抗體