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缺陷沉默抑制因子3抗體

英文名稱 SDS3
中文名稱 缺陷沉默抑制因子3抗體
別    名 2400003N08Rik; 2410008L21Rik; 45 kDa Sin3 associated polypeptide; 45 kDa Sin3-associated polypeptide; AU067672; FLJ00052; FLJ13739; MGC104711; mSds3; RGD1305986; SAP45; SDS3; SDS3, yeast, homolog of; SDS3_HUMAN; Sin3 histone deacetylase corepressor complex component SDS3; Sin3A associated protein 45kDa; Suds3; Suppressor of defective silencing 3; Suppressor of defective silencing 3 homolog (S cerevisiae); Suppressor of defective silencing 3 homolog (SDS3 S cerevisiae); Suppressor of defective silencing 3 protein homolog.
    
說 明 書 0.2ml  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Cow, Monkey, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDS3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]

Function:
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. May have a potential role in tumor suppressor pathways (By similarity). May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.

Tissue Specificity:
Expressed in various cancer cell ines.

Similarity:
Belongs to the SDS3 family.

Gene ID:
64426

Database links:

Entrez Gene: 64426 Human

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xy-10320R    H3N1 hemagglutinin流感病毒H3N1血凝素抗體
xy-12309R    Hoxb3同源盒蛋白HoxB3抗體
xy-12335R    HFE遺傳性血色病蛋白相關(guān)蛋白1抗體
xy-12315R    HHATL甘油吸收/轉(zhuǎn)運(yùn)蛋白GUP1抗體
xy-12316R    HHIPHHIP蛋白抗體
xy-15458R    Hephaestin亞鐵氧化酶抗體
xy-15459R    HERC1 鳥苷酸釋放因子p532蛋白抗體
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xy-15461R    HERC3HERC3 E3泛素蛋白連接酶抗體
xy-15462R    HERC4HERC4 E3泛素蛋白連接酶抗體
xy-15463R    HERC6HERC6 E3泛素蛋白連接酶抗體
xy-15464R    HERPUD1MMF誘導(dǎo)片段蛋白1抗體
xy-15465R    HERPUD2HERPUD蛋白家族成員2抗體
xy-15472R    HGD尿黑酸氧化酶抗體
xy-15473R    HGS 肝細(xì)胞生長(zhǎng)調(diào)節(jié)因子酪氨酸激酶底物抗體
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xy-15482R    hHR23b紫外切除修復(fù)蛋白R(shí)AD23B抗體
xy-15483R    HIBADH3-羥基異丁酸脫氫酶抗體
xy-15484R    HIBCH Hib乙酰輔酶A水解酶抗體
xy-15485R    HIC1腫瘤異常甲基化蛋白1抗體
xy-15486R    HIC2 腫瘤異常甲基化蛋白2抗體
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xy-15466R    HERV-FRD 人內(nèi)源性逆轉(zhuǎn)錄病毒膜糖蛋白2抗體
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xy-15451R    Hepatitis C virus NS5B丙型肝炎病毒NS5B抗體