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轉運蛋白SEC61A抗體

英文名稱 SEC61A
中文名稱 轉運蛋白SEC61A抗體
別    名 chunp6898; fb62c11; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; Protein transport protein Sec61 subunit alpha isoform 1; S61A1_HUMAN; SEC 61; SEC 61A; Sec61 alpha 1; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha-1; SEC61; Sec61 homolog; SEC61A1; sec61aa.
  
說 明 書 0.2ml  
研究領域 細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC61A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

Function:
Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

Subunit:
Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the secY/SEC61-alpha family.

Gene ID:
29927xy-4964R    human secretory IgA人分泌型免疫球蛋白A
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xy-1363R    AIF1離子鈣接頭蛋白抗體
xy-9464R    IRX4Iroquois同源蛋白4抗體
xy-6877R    IFRD1干擾素相關發(fā)育調節(jié)蛋白1抗體（神經(jīng)生長因子誘導蛋白PC4）
xy-6870R    ILP2抑制細胞凋亡樣蛋白2抗體
xy-4750R    IFITM1干擾素誘導跨膜蛋白1抗體
xy-8690R    IFI44干擾素誘導蛋白44抗體
xy-6471R    ITPR35-三磷酸肌醇受體3抗體
xy-15525R    IFNW1干擾素omega 1蛋白抗體
xy-15521R    IFNA7干擾素alpha 7蛋白抗體
xy-0787R    IFN-Beta干擾素β抗體
xy-3529R    ID1DNA結合抑制因子1抗體
xy-8676R    IFI-202γ干擾素誘導蛋白202抗體
xy-0788R    intestinal FABP/IFABP/FABP2腸型脂肪酸結合蛋白抗體
xy-1291R    ING1生長抑制因子基因1抗體
xy-0780R    IL-8/CXCL8白介素8抗體
xy-0317R    ILK-1整合素連接激酶-1抗體
xy-3235R    phospho-IKK alpha (Ser176 + Ser180)磷酸化KB抑制蛋白激酶α抗體
xy-3236R    Phospho-IKK alpha(Ser180) + IKK beta(Ser181)磷酸化KB抑制蛋白激酶α/β抗體
xy-3237R    Phospho-IKK alpha/beta (Ser176 + Ser180)磷酸化KB抑制蛋白激酶α/β抗體
xy-15563R    IFT46細胞纖毛內轉運同源蛋白46抗體
xy-2459R    IL-10RA白細胞介素-10受體a抗體
xy-2460R    IL-13Ra1白細胞介素-13受體a1抗體
xy-4015R    IRGM免疫相關鳥苷三磷酸酶基因抗體
xy-2461R    IL-13Ra2白細胞介素-13受體a2抗體
xy-2450R    I-309嗜酸粒細胞趨化蛋白CCL1抗體
xy-3226R    phospho-IGF1R (Tyr1161)磷酸化胰島素樣生長因子1受體抗體
xy-0018R    IDE胰島素降解酶抗體
xy-1789R    IL-12白介素12抗體