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SAPS結(jié)構(gòu)域家族2抗體

英文名稱 SAPS2
中文名稱 SAPS結(jié)構(gòu)域家族2抗體
別    名 SAPS 2; dJ579N16.1; KIAA0685; PP6R2; SAP190; SAPS domain family, member 2.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 130 and 150kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAPS2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

Function:
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.

Subunit:
Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6C and NFKBIE. Interacts with ANKRD28.xy-15591R    LETM1LETM1蛋白抗體
xy-1810R    LDHA乳酸脫氫酶抗體
xy-1532R    phospho-LKB1 (Thr363)磷酸化絲氨酸/蘇氨酸蛋白激酶抗體
xy-1526R    Laminin Beta 1層粘連蛋白β1抗體
xy-0976R    LPLUNC1鼻咽癌癌基因抗體
xy-1458R    LIFR白血病抑制因子受體抗體
xy-1839R    lamin A + C核纖層蛋白A抗體
xy-1840R    Lamin B核纖層蛋白B抗體(細(xì)胞核膜標(biāo)志物)
xy-1841R    lamin A + C核纖層蛋白A/C抗體
xy-1845R    LRIG2LRIG2抗體
xy-1843R    LEF-1淋巴增強(qiáng)因子-1抗體
xy-1844R    LRIG1LRIG1抗體
xy-1846R    LRIG3LRIG3抗體
xy-1617R    LI-cadherin肝腸鈣粘連蛋白抗體
xy-1842R    Layilin透明質(zhì)酸受體抗體
xy-9649R    C17orf8217號(hào)染色體開(kāi)放閱讀框82抗體
xy-11874R    LMCD1轉(zhuǎn)錄因子LMCD1抗體
xy-12336R    Ly76淋巴細(xì)胞抗原76抗體
xy-9509R    LRP15富含亮氨酸重復(fù)序列LRP15抗體
xy-11213R    LRRTM1富含亮氨酸重復(fù)跨膜神經(jīng)元蛋白1抗體
xy-8561R    Laminin 2 alpha層粘蛋白α2抗體
xy-6762R    LIPG內(nèi)皮脂肪酶抗體
xy-4206R    sLOX 1可溶性凝集素樣氧化低密度脂蛋白受體1抗體
xy-7504R    Laminin Beta 2層粘連蛋白β2抗體
xy-7516R    LECT1白細(xì)胞衍生化學(xué)吸引素抗體
xy-8430R    LMO2T淋巴細(xì)胞易位蛋白2抗體
xy-11463R    Liprin alpha 1酪氨酸磷酸酶受體相互作用蛋白Liprin α1抗體
xy-4245R    LONP1線粒體離子肽酶1抗體
xy-6230R    LC3C微管相關(guān)蛋白輕鏈3C抗體
xy-5705R    LZTS1假定腫瘤抑制亮氨酸拉鏈蛋白1抗體
xy-3827R    LDHC(Cancer,testis antigen 32)乳酸脫氫酶LDH-C（腫瘤/睪丸抗原32）抗體
xy-6090R    LUCA15腫瘤抑制基因LUCA15抗體
xy-9193R    LST1淋巴細(xì)胞特異性轉(zhuǎn)運(yùn)蛋白1抗體
xy-4118R    LEO1RNA聚合酶相關(guān)蛋白LEO1抗體
xy-5408R    Phospho-LRP6(Thr1479)磷酸化低密度脂蛋白受體相關(guān)蛋白6抗體
xy-5406R    phospho-LCK(Tyr394)磷酸化淋巴細(xì)胞特異性蛋白酪氨酸激酶抗體
xy-4117R    LRP5低密度脂蛋白受體相關(guān)蛋白5抗體
xy-5407R    phospho-LRP5(Thr1492)磷酸化低密度脂蛋白受體相關(guān)蛋白5抗體
xy-5409R    phospho-LRP1(Ser4523)磷酸化低密度脂蛋白受體相關(guān)蛋白1抗體