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SAPS結(jié)構(gòu)域家族3抗體

英文名稱 SAPS3
中文名稱 SAPS結(jié)構(gòu)域家族3抗體
別    名 C11orf23; Chromosome 11 open reading frame 23; KIAA1558; PP6R3; PP6R3_HUMAN; PPP6R3; Protein phosphatase 6 regulatory subunit 3; SAP190; SAPL; SAPLa; SAPS domain family member 3; SAPS domain family, member 3; Serine/threonine-protein phosphatase 6 regulatory subunit 3; Sporulation induced transcript 4 associated protein SAPL; Sporulation-induced transcript 4-associated protein SAPL.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Chicken, Horse, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SAPS3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

Function:
Regulatory subunit of protein phospatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.

Subunit:
Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6C and ANKRD28.

Subcellular Location:
Cytoplasm. Nucleus.xy-3948R    LKB1蘇氨酸蛋白激酶LKB1抗體
xy-9364R    LMP7低分子量蛋白7抗體
xy-3861R    LIM protein脂肪瘤相關(guān)蛋白抗體
xy-10374R    Laminin subunit beta-4層粘連蛋白β4抗體
xy-10370R    GnRH-associated peptide I黃體激素釋放激素/促性腺激素釋放激素抗體
xy-15492R    LOX蛋白賴氨酸-6-氧化酶抗體
xy-15500R    LTK白細(xì)胞酪氨酸激酶受體抗體
xy-12386R    LMX1A同源盒轉(zhuǎn)錄因子LMX1A抗體
xy-12413R    LTBP1轉(zhuǎn)化生長因子β1結(jié)合蛋白1抗體
xy-12390R    Manic Fringe狂躁基因同源蛋白MFNG抗體
xy-12391R    Mib1E3泛素蛋白連接酶MIB1抗體
xy-12396R    MAML1主導(dǎo)控制樣蛋白1抗體
xy-12397R    MAML2主導(dǎo)控制樣蛋白2抗體
xy-12405R    MAPK6絲裂原活化蛋白激酶6抗體
xy-12375R    phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174)磷酸化絲氨酸/蘇氨酸蛋白激酶MST4,MST3,STK25抗體
xy-12372R    MEGF10表皮生長因子樣蛋白Megf10抗體
xy-15379R    MPP4MPP4蛋白抗體
xy-10319R    MCM7/CDC47微小染色體維持缺陷蛋白7抗體
xy-9291R    MUL1E3泛素連接酶MUL1抗體
xy-3859R    MAGP2纖微絲相關(guān)糖蛋白2抗體
xy-2353R    Mast Cell Chymase肥大細(xì)胞類糜蛋白酶1抗體
xym-2059M    Metronidazole(1C2)甲硝唑單克隆抗體
xy-3834R    MrpL12線粒體核糖體蛋白L12抗體
xy-3835R    MrpL39線粒體核糖體蛋白L39
xy-3788R    Mitochondrial Pyruvate dehydrogenase kinase 1丙酮酸脫氫酶激酶1抗體
xy-4138R    MAPK11絲裂原活化的蛋白激酶p38β抗體
xy-5141R    Matrin 3核基質(zhì)蛋白3抗體
xy-7335R    MHC class I組織相容性復(fù)合體蛋白1抗體
xy-8481R    MHC Class II組織相容性復(fù)合體蛋白2抗體
xy-3950R    MLX轉(zhuǎn)化因子樣蛋白4抗體
xy-3952R    MT-ND5NADH復(fù)合體5抗體
xy-9178R    MTM1肌微管素1抗體
xy-9179R    MLF1 髓細(xì)胞性白血病蛋白1抗體
xy-5413R    phospho-MEK1 (Thr386)磷酸化絲裂原活化蛋白激酶1抗體
xy-4107R    MHC Class II組織相容性復(fù)合體2抗體
xy-5329R    Phospho-mTOR (Tyr144)磷酸化雷帕霉素靶蛋白抗體