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肌氨酸脫氫酶抗體

英文名稱 SARDH
中文名稱 肌氨酸脫氫酶抗體
別    名 DMGDHL1; SARDH_HUMAN; Sarcosine dehydrogenase.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SARDH
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]

Subcellular Location:
Mitochondrion matrix (By similarity)

DISEASE:
Sarcosinemia (SARCOS) [MIM:268900]: A metabolic disorder characterized by an increased concentration of sarcosine in plasma and an increased excretion of sarcosine in urine. Sarcosinemia is most probably a benign condition without significant clinical problems. Some reports have associated sarcosinemia with mental retardation and neurologic problems.

Similarity:
Belongs to the GcvT family.

Gene ID:
1757

Database links:

Entrez Gene: 1757 Human

Entrez Gene: 114123 Rat

SwissProt: Q9UL12 Human

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xy-11353R    Munc13 神經(jīng)突觸前膜胞內(nèi)蛋白13抗體
xy-11322R    Membralin高度保守基因相關(guān)蛋白Membralin抗體
xy-11320R    MNX1運(yùn)動(dòng)神經(jīng)元及胰腺同源蛋白1抗體
xy-11184R    MOBP少突膠質(zhì)細(xì)胞髓鞘相關(guān)蛋白抗體
xy-11189R    MRCK alphaCDC42結(jié)合蛋白激酶α抗體（MRCKα）
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xy-3503R    Mre11DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3293R    Phospho-Mre11 (Ser676)磷酸化DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3504R    MST1蛋白激酶MST抗體
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xy-3295R    Phospho-MYL(Ser19)磷酸化肌球蛋白輕鏈2抗體
xy-3505R    Myt1髓鞘轉(zhuǎn)錄因子1抗體
xy-1352R    MCL1髓樣細(xì)胞白血病-1抗體
xy-1369R    MAP2微管相關(guān)蛋白2抗體
xy-9470R    MEF2B肌細(xì)胞增強(qiáng)因子2B抗體
xy-9471R    MESP1心血管發(fā)育中胚層相關(guān)蛋白1抗體
xy-9440R    MTA2轉(zhuǎn)移相關(guān)蛋白2抗體
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xy-9313R    MAP-9微管相關(guān)蛋白9抗體
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