氨基丁酸轉(zhuǎn)運(yùn)蛋白VGAT抗體 返回列表頁

氨基丁酸轉(zhuǎn)運(yùn)蛋白VGAT抗體

英文名稱 SLC32A 1
中文名稱 氨基丁酸轉(zhuǎn)運(yùn)蛋白VGAT抗體
別    名 VGAT; bA122O1.1; GABA and glycine transporter; hVIAAT; SLC32A 1; solute carrier family 32 (GABA vesicular transporter) member 1; Solute carrier family 32 member 1; Vesicular GABA Amino Acid Transporter; Vesicular GABA transporter; Vesicular inhibitory amino acid transporter; VGAT; VIAAT; VIAAT_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC32A 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure

Function:
Involved in the uptake of GABA and glycine into the synaptic vesicles.

Subcellular Location:
Cytoplasmic vesicle membrane; Multi-pass membrane protein.

Tissue Specificity:
Retina. Expressed throughout the horizontal cells or more specifically at the terminals.xy-3285R    Phospho-MYPT1 (Ser507)磷酸化肌球蛋白磷酸酶抗體
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xy-3287R    Phospho-MYPT1(Thr696)磷酸化肌球蛋白磷酸酶抗體
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xy-3275R    Phospho-MEK6 (Ser207)磷酸化絲裂原活化蛋白激酶MKK6抗體
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xy-2029R    Morphine嗎啡抗體
xy-1676R    MG雞毒支原體抗體
xy-8520R    MtTF1線粒體轉(zhuǎn)錄因子1抗體
xy-1595R    MAD1有絲分裂抑制缺陷蛋白1抗體
xy-9344R    MARCH10膜相關(guān)環(huán)指蛋白10抗體
xy-6863R    MALT1粘膜相關(guān)淋巴組織淋巴瘤轉(zhuǎn)運(yùn)蛋白1抗體
xy-0642R    MAdCAM-1粘膜血管定居因子抗體
xy-0792R    Maspin抑癌基因抗體
xy-0671R    MCK10神經(jīng)上皮酪氨酸激酶/乳腺癌激酶10抗體
xy-0832R    MICAMHC I類鏈相關(guān)蛋白A/組織相容性復(fù)合物MHCIa抗體
xy-0762R    Midnolin中腦核仁蛋白抗體
xy-1044R    MIF巨噬細(xì)胞移動抑制因子抗體
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xy-1150R    muscarinic Acetylcholine Receptor 1毒蕈堿型乙酰膽堿受體M1抗體
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xy-1041R    MEK1 + MEK2絲裂原活化蛋白激酶激酶1抗體
xy-0223R    MEK2絲裂原活化蛋白激酶激酶2抗體
xy-0531R    Matriptase蛋白裂解酶（一種新的癌基因）抗體
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