糖尿病相關(guān)同源結(jié)構(gòu)域蛋白SIX5抗體 返回列表頁

糖尿病相關(guān)同源結(jié)構(gòu)域蛋白SIX5抗體

英文名稱 SIX5
中文名稱 糖尿病相關(guān)同源結(jié)構(gòu)域蛋白SIX5抗體
別    名 BOR2; DM locus associated homeodomain protein; DM locus-associated homeodomain protein; DMAHP; Dystrophia myotonica associated homeodomain protein; Homeobox protein SIX5; Sine oculis homeobox homolog 5; sine oculis related homeobox 5 homolog (Drosophila); SIX homeobox 5; SIX5; SIX5_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  糖尿病  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIX5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this gene are a cause of branchiootorenal syndrome type 2. [provided by RefSeq, Jul 2009]

Function:
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in adult but not in fetal eyes. Found in corneal epithelium and endothelium, lens epithelium, ciliary body epithelia, cellular layers of the retina and the sclera.xy-9756R    ANKRD26錨蛋白重復(fù)結(jié)構(gòu)域蛋白26抗體
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xy-2409R    Amphiphysin神經(jīng)元突觸前膜蛋白抗體
xy-2415R    Ankyrin G錨定蛋白G抗體
xy-0189R    Actin肌動蛋白α/α-SMA/α Actin抗體
xy-1208R    ADAMTS1整合素樣金屬蛋白酶與凝血酶1型抗體
xy-0733R    ADAMTS7(NT)整合素樣金屬蛋白酶與凝血酶1型-7抗體 (N端抗體)
xy-0433R    ADAMTS7整合素樣金屬蛋白酶與凝血酶1型-7抗體
xy-1114R    beta Adducin內(nèi)收蛋白抗體
xy-1164R    ADFP脂肪組織分化相關(guān)蛋白抗體
xy-0610R    Adiponectin Receptor 1脂聯(lián)素受體1抗體
xy-0090R    ADM R腎上腺髓質(zhì)素受體抗體
xy-0471R    Adiponectin脂聯(lián)素抗體
xy-0007R    ADM腎上腺髓質(zhì)素抗體
xy-1225R    Adenosine A3 Receptor腺苷受體A3抗體
xy-1062R    ADRA2ADRA2腎上腺素能受體2抗體
xy-0498R    ADRB1腎上腺素能受體β1抗體
xy-0947R    ADRB2腎上腺素能受體β2/β2-AR抗體
xy-1158R    AGEs晚期糖基化終末產(chǎn)物抗體
xy-1223R    Aggrecan1軟骨蛋白聚糖抗體
xy-9516R    ALAS-E5-氨基乙酰丙酸合酶1抗體
xy-1282R    ASPP1p53凋亡刺激蛋白1抗體
xy-1283R    ASPP2P53凋亡刺激蛋白2抗體
xy-0801R    ARIP2B激活素受體2B抗體
xy-2509R    AIMP2AIMP2抗體
xy-2511R    ACHE乙酰膽堿酶抗體
xy-9527R    ALAS15-氨基乙酰丙酸合酶1抗體
xy-1697R    alpha Defensin 1防御素α1/3抗體
xy-1727R    ABCG4ABC膜轉(zhuǎn)運蛋白抗體
xy-2221R    ATEXPA10植物延長蛋白（擬南芥）
xy-2251R    A RafA-Raf抗體
xy-3371R    Phospho-A Raf(Ser299)磷酸化A-Raf抗體
xy-9517R    AMPD3紅細胞腺苷脫氨酶3抗體
xy-2410R    ABP雄激素結(jié)合蛋白抗體
xy-1576R    ALR肝再生增強因子抗體
xy-0112R    Amyloid Precursor ProteinAPP/ABPP淀粉樣肽前體蛋白抗體
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