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SKIP蛋白抗體

英文名稱 SKIP
中文名稱 SKIP蛋白抗體
別    名 43 kDa form skeletal muscle and kidney enriched inositol phosphatase; Inositol polyphosphate 5-phosphatase K; INP5K_HUMAN; INPP5K; muscle and kidney-enriched inositol phosphatase; PPS; skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase.
  
說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Function:
Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. May negatively regulate assembly of the actin cytoskeleton.

Subcellular Location:
Endoplasmic reticulum. Following stimulation with EGF, translocates to membrane ruffles.

Tissue Specificity:
Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.

Similarity:
Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.

Gene ID:
51763xym-1622M    AFP(A4)甲胎蛋白單克隆抗體(檢測(cè))
xy-1477R    ARFIP1 ADP核糖基化因子結(jié)合蛋白1抗體
xy-1416R    AHR芳香烴受體抗體
xy-1528R    ATRN吸引素抗體
xy-1627R    ABCA1腺苷三磷酸結(jié)合盒轉(zhuǎn)運(yùn)體A1抗體
xy-2056R    AKT2蛋白激酶B2
xy-0677R    Angiopoietin 2血管生成素2抗體
xy-0114R    Aromatase芳香化酶/細(xì)胞色素P450/雌激素合成酶抗體
xy-1456R    Adenosine Receptor A2a腺苷A2A受體抗體
xy-1473R    AKAP95蛋白激酶A錨定蛋白95抗體
xy-4189R    ASBT頂膜鈉依賴性膽鹽轉(zhuǎn)運(yùn)體蛋白抗體
xy-4195R    ADAM8去整合素樣金屬蛋白酶8抗體
xy-11386R    AADACL3芳香乙酰胺脫乙?；笜拥鞍?抗體
xy-12444R    ACN9ACN9蛋白抗體
xy-2167R    ADAR1 (N-terminus)雙鏈RNA腺苷酸脫氨基酶抗體（N端）
xy-2771R    AMPK alpha 2腺苷單磷酸活化蛋白激酶α2抗體
xy-2778R    ADK腺苷酸激酶抗體
xy-13780R    A2ML1α2巨球蛋白樣蛋白1抗體 α2ML1
xy-13814R    APR3細(xì)胞凋亡相關(guān)蛋白3抗體
xy-10196R    Actin肌動(dòng)蛋白α/α-SMA/α Actin抗體
xy-12331R    ABCB7ATP結(jié)合蛋白家族7抗體
xy-12349R    ASCL2ASCL2蛋白抗體
xy-12534R    phospho-Ataxin 1(Ser775)磷酸化脊髓小腦失調(diào)癥蛋白1抗體
xy-12535R    phospho-ATF1 (Ser63)磷酸化活化轉(zhuǎn)錄因子1抗體
xy-12536R    phospho-ATF2 (Ser480)磷酸化活化復(fù)制因子2抗體
xy-12537R    phospho-ATF2 (Thr51 + Thr53)磷酸化活化復(fù)制因子2抗體
xy-12538R    phospho-ATF2 (Thr69 + Thr51)磷酸化活化復(fù)制因子2抗體
xy-12539R    phospho-ATF2 (Thr73 + Thr55)磷酸化活化復(fù)制因子2抗體
xy-12541R    phospho-ATF2 (Thr71 + Thr53)磷酸化活化復(fù)制因子2抗體
xy-12540R    phospho-ATF2(Thr71)磷酸化活化復(fù)制因子2抗體
xy-12542R    ATF5活化轉(zhuǎn)錄因子5抗體
xy-12543R    ATF6 beta活化轉(zhuǎn)錄因子6β抗體
xy-12544R    ATICAICAR甲?；D(zhuǎn)移酶抗體
xy-12545R    phospho-ATM (Ser794)磷酸化毛細(xì)血管擴(kuò)張性共濟(jì)失調(diào)癥突變蛋白抗體
xy-12546R    ATP5EATP5E蛋白抗體
xy-12547R    ATP5G2ATP5G2蛋白抗體
xy-12548R    ATP6V0D2ATP6V0D2蛋白抗體