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SKT蛋白抗體

參   考   價: 14

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

廠商性質(zhì)生產(chǎn)商

所  在  地上海

更新時間:2015-06-12 08:49:44瀏覽次數(shù):390次

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SKT蛋白抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.

SKT蛋白抗體

英文名稱 SKT
中文名稱 SKT蛋白抗體
別    名 DKFZP761L0424; KIAA1217; Likely orthologue of Mus musculus enhancer trap locus 4; Sickle tail protein homolog; SKT; SKT_HUMAN.
  
說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the

PubMed PubMed
產(chǎn)品介紹 background:
SKT is a 1,943 amino acid protein that localizes to cytoplasm. The SKT protein is required for normal development of intervertebral disks. Existing as seven alternatively spliced isoforms, the SKT gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10p12.2. Spanning nearly 135 million base pairs, chromosome 10 makes up approximay 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. 

Function:
Required for normal development of intervertebral disks.

Subcellular Location:
Cytoplasm.

Database links:

Entrez Gene: 56243 Human

SwissProt: Q5T5P2 Human

Unigene: 445885 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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