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Skuld蛋白抗體

英文名稱 Skuld
中文名稱 Skuld蛋白抗體
別    名 CG9936-PC isoform C; Cg9936-pd isoform d; Jlkjlkj; MED13_DROME; Med13; Mediator complex subunit 13; Pap/DTRAP240; Protein blind spot; skd; Transcriptional coactivator blind spot; Trap240.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 發(fā)育生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Fruit fly
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 280kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Fruit fly Skuld
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Sklud is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development.

Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development. Required for activated transcription of the MtnB and MtnD genes.

Subunit:
Component of the Cdk8 module of the Mediator complex, composed of CycC, Cdk8, kto and skd.

Subcellular Location:
Nuclearxy-0800R    Angiopoietin-1血管生成素-1抗體
xy-0398R    Annexin V膜粘連蛋白5抗體
xy-0450R    Annexin V重組膜粘連蛋白5抗體
xy-1228R    alpha Adaptin銜接蛋白α-Adaptin抗體
xy-0058R    APAF1(CT)凋亡蛋白活性因子-1抗體（C端）
xy-0059R    APAF1(NT)凋亡蛋白活性因子-1抗體（N端）
xy-0662R    ABCG2三磷酸腺苷結(jié)合轉(zhuǎn)運(yùn)蛋白G超家族成員2抗體
xy-0167R    APOE載脂蛋白E抗體
xy-0112M    Amyloid Precursor Protein淀粉樣肽前體蛋白抗體
xy-0261R    Aquaporin 2水通道蛋白-2抗體
xy-0045M    AGT血管緊張素原抗體
xy-0118R    Androgen receptor雄激素受體抗體
xy-2438R    AVEN細(xì)胞死亡調(diào)節(jié)蛋白抗體(凋亡、半胱胺酸蛋白酶激活抑制劑)
xy-2439R    Axin1軸蛋白1抗體
xy-4011R    ATG9B自噬相關(guān)蛋白9B抗體
xy-4012R    Apg12自噬相關(guān)蛋白12抗體
xy-3864R    ATG13自噬相關(guān)蛋白13抗體
xy-4013R    ATG3自噬相關(guān)蛋白3抗體
xy-4191R    ADAMTS4整合素樣金屬蛋白酶與凝血酶4型抗體
xy-1648R    phospho-ATF2 (Ser490/498)磷酸化活化復(fù)制因子2抗體
xy-1649R    phospho-Amyloid Precursor Protein (Tyr757)磷酸化APP(Tyr757)淀粉樣肽前體蛋白抗體
xy-2919R    ACTR絲氨酸/蘇氨酸蛋白激酶ATR抗體
xy-5849R    ADAM18去整合素樣金屬蛋白酶18抗體
xy-1634R    ATF6活化轉(zhuǎn)錄因子6抗體
xy-1546R    AP2 beta銜接蛋白β抗體
xy-1600R    Gamma-Adaptin銜接蛋白γ/γ-Adaptin抗體
xy-2060R    AQP9水通道蛋白-9抗體
xy-1631R    Annexin A3膜粘連蛋白A3抗體
xy-1564R    Annexin IV膜粘連蛋白 A4抗體
xy-12487R    APG8A自噬相關(guān)蛋白8A抗體
xy-3043R    phospho-Akt (Thr450)磷酸化蛋白激酶B抗體
xy-5551R    phospho-AMPK alpha-1 (Thr198)磷酸化腺苷單磷酸活化蛋白激酶α1抗體
xy-2720R    phospho-Akt(Thr308)磷酸化蛋白激酶B抗體
xy-15407R    APOBEC3G脫氧胞苷脫氨酶蛋白抗體
xy-13637R    AKAP13蛋白激酶錨定蛋白13抗體
xy-13638R    AP1M2AP-1μ2抗體