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轉(zhuǎn)錄因子Sp2抗體

英文名稱 SP2 transcription factor
中文名稱 轉(zhuǎn)錄因子Sp2抗體
別    名 Kiaa0048; OTTHUMP00000196580; SP2; SP2_HUMAN; SPECIFICITY PROTEIN 2; Transcription factor Sp2.
 
說(shuō) 明 書 0.2ml  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  鋅指蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SP2 transcription factor
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]

Function:
Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.

Database links:

Entrez Gene: 6668 Human

Entrez Gene: 78912 Mouse

Omim: 601801 Human

SwissProt: Q02086 Human

SwissProt: Q9D2H6 Mouse

Unigene: 514276 Humanxy-12962R    phospho-AKT1 (Ser246)磷酸化蛋白激酶AKT1抗體
xy-15963R    phospho-AKT1/3 (Tyr473)磷酸化蛋白激酶B抗體
xy-15967R    phospho-alpha 1 Sodium Potassium ATPase (Tyr260) 磷酸化鈉鉀ATP酶蛋白a1抗體
xy-15968R    phospho-alpha Adducin(Ser436)磷酸化內(nèi)收蛋白a1抗體
xy-12972R    phospho-AMPK alpha 1 (Ser487)磷酸化腺苷單磷酸活化蛋白激酶α1抗體
xy-12973R    phospho-AMPK alpha 2 (Ser345)磷酸化腺苷單磷酸活化蛋白激酶α2抗體
xy-12976R    ASAH1酸性神經(jīng)酰胺酶1抗體
xy-13357R    ADRM1粘附調(diào)節(jié)分子1抗體
xy-12488R    Aphrodisin氣味結(jié)合蛋白抗體
xy-5110R    ALDH2乙醛脫氫酶2抗體
xy-5127R    Annexin A10膜粘連蛋白10抗體
xy-5123R    Anterior Gradient 2前梯度同源蛋白2抗體
xy-5133R    ALDH1B1乙醛脫氫酶5抗體
xy-5139R    ALF通用轉(zhuǎn)錄因子IIA樣因子抗體
xy-4009R    ATG4D自噬相關(guān)蛋白4D抗體
xy-4010R    ATG9A自噬相關(guān)蛋白9A抗體
xy-3976R    Aldolase C醛縮酶C抗體
xy-3977R    Aspartate Aminotransferase谷草轉(zhuǎn)氨酶抗體
xy-5013R    ABCG5三磷酸腺苷結(jié)合轉(zhuǎn)運(yùn)蛋白G超家族成員5抗體
xy-5014R    ABCG8三磷酸腺苷結(jié)合轉(zhuǎn)運(yùn)蛋白G超家族成員8抗體
xy-5015R    ACADL?；o酶A脫氫酶長(zhǎng)鏈抗體
xy-4047R    ACADM?；o酶A脫氫酶中鏈抗體
xy-4048R    ACADS?；o酶A脫氫酶短鏈抗體
xy-5021R    ACOX1過氧化物酶?；o酶A氧化酶1抗體
xy-5437R    phospho-ASK1 (Ser1033)磷酸化細(xì)胞凋亡信號(hào)調(diào)節(jié)激酶1抗體
xy-7696R    AXUD1轉(zhuǎn)化生長(zhǎng)因子β誘導(dǎo)蛋白3抗體（半胱氨酸和絲氨酸富含核蛋白1）
xy-2751R    Aurora A+B+C有絲分裂激酶A/B/C抗體
xy-2752R    ATK蛋白酪氨酸激酶ATK抗體
xy-5022R    ACSL1長(zhǎng)鏈脂肪酸輔酶A連接酶1/2抗體
xy-5030R    ACOX2過氧化物酶?；o酶A氧化酶2抗體
xy-5019R    ACAT1膽固醇?；D(zhuǎn)移酶1抗體
xy-3021R    phospho-ALK (Tyr1278 + Tyr1282 + Tyr1283)磷酸化間變型淋巴瘤激酶抗體
xy-3006R    phospho-arfaptin 2 (Ser260)磷酸化ADP核糖基化因子結(jié)合蛋白2抗體
xy-3049R    Phospho-Aurora B (Thr232) + Aurora C (Thr198)磷酸化有絲分裂激酶B/C抗體
xy-3001R    phospho-Acinus (Ser1180)磷酸化腺泡Acinus蛋白抗體
xy-3002R    phospho-ADRB2 (Ser346)磷酸化腎上腺素能受體β2抗體
xy-2731R    APSAPS抗體
xy-6020R    ACVRL1激活素受體樣激酶1抗體
xy-6018R    ACVR1B激活素A受體1B抗體
xy-3004R    phospho-Androgen Receptor (Ser597)磷酸化雄激素受體抗體
xy-3005R    phospho-A Raf (Ser214)磷酸化A-Raf抗體
xy-6021R    ASAH2?；拾贝济擋Ｃ?抗體
xy-6022R    ASAM脂肪細(xì)胞特異性粘附分子抗體
xy-11392R    AAV5 capsid VP2 protein腺相關(guān)病毒5抗體
xy-3968R    AMPK gamma 3腺苷酸活化蛋白激酶γ3抗體
xy-3967R    AMPK beta 2腺苷單磷酸活化蛋白激酶β2抗體
xy-5173R    phospho-APC1 (Ser355)磷酸化細(xì)胞周期末期促進(jìn)復(fù)合蛋白APC1抗體
xy-4090R    ANAPC1細(xì)胞周期末期促進(jìn)復(fù)合蛋白APC1抗體
xy-4089R    phospho-AKT2 (Ser474)磷酸化蛋白激酶B2抗體
xy-5165R    phospho-APBB1 (Ser175)磷酸化鐵蛋白Fe65抗體
xy-5166R    phospho-APBB1 (Ser347)磷酸化鐵蛋白Fe65抗體
xy-5167R    phospho-Amyloid Precursor Protein (Thr743)磷酸化APP淀粉樣肽前體蛋白抗體
xy-5168R    phospho-Amyloid Precursor Protein (Ser730)磷酸化APP淀粉樣肽前體蛋白抗體
xy-5169R    phospho-ATF2 (Ser322)磷酸化活化復(fù)制因子2抗體
xy-5172R    phospho-ATF2 (Thr51)磷酸化活化復(fù)制因子2抗體
xy-5174R    phospho-APC1 (Ser377)磷酸化細(xì)胞周期末期促進(jìn)復(fù)合蛋白APC1抗體