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精子發(fā)生相關(guān)蛋白18抗體

參   考   價: 15

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

廠商性質(zhì)生產(chǎn)商

所  在  地上海

更新時間:2015-06-12 09:05:43瀏覽次數(shù):205次

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精子發(fā)生相關(guān)蛋白18抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.

精子發(fā)生相關(guān)蛋白18抗體

英文名稱 SPATA18
中文名稱 精子發(fā)生相關(guān)蛋白18抗體
別    名 1700067I02Rik; FLJ32906; MGC93900; Mieap; mitochondria eating protein; SPATA18; Spermatogenesis associated 18; spermatogenesis associated 18 homolog (rat); Spermatogenesis associated protein 18; Spermatogenesis-associated protein 18; SPETEX1; SPT18_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Chimpanzee, Macaque Monkey, Gorilla, Orangutan
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPATA18
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SPATA18 is a 538 amino acid protein that is thought to play a role in cell differentiation during spermatogenesis, particularly during development from late elongate spematids to mature spermatozoa. Localizing to cytoplasm, SPATA18 is encoded by a gene that maps to human chromosome 4q12. Chromosome 4 represents approximay 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Function:
Potential role in spermatogenesis, especially in cell differentiation from late elongate spematids to mature spermatozoa.

Subunit:
Interacts (via coiled-coil domains) with BNIP3L (via BH3 domain). Interacts (via coiled-coil domains) with BNIP3 (via BH3 domain).

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the MIEAP family.

Gene ID:
132671

Database links:

Entrez Gene: 132671 Human

Entrez Gene: 289586 Rat

Omim: 612814 Human

SwissProt: Q8TC71 Human

SwissProt: Q6AYL6 Rat

Unigene: 527090 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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