Shroom 3蛋白抗體 返回列表頁

Shroom 3蛋白抗體

英文名稱 Shroom 3
中文名稱 Shroom 3蛋白抗體
別    名 APXL3; hShrmL; MSTP013; Protein Shroom3; Shrm; Shrm3; SHRM3_HUMAN; ShrmL; Shroom family member 3; Shroom-related protein; shroom3.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 217kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Shroom 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011]

Function:
Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays.

Subunit:
Interacts with F-actin.

Subcellular Location:
Cell junction; adherens junction. Cytoplasm > cytoskeleton. Colocalizes with F-actin in stress fibers and adherens junctions.

Similarity:
Belongs to the shroom family.
Contains 1 ASD1 domain.
Contains 1 ASD2 domain.
Contains 1 PDZ (DHR) domain.

Gene ID:
57619

Database links:

Entrez Gene: 57619 Human

Omim: 604570 Human

SwissProt: Q8TF72 Human

Unigene: 702168 Human

Important Note:
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xy-9772R    C10orf9310號染色體開放閱讀框93抗體
xy-9773R    C10orf6310號染色體開放閱讀框63抗體
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xy-9777R    C1orf1251號染色體開放閱讀框125抗體
xy-9778R    C1orf1291號染色體開放閱讀框129抗體
xy-9779R    C1orf1591號染色體開放閱讀框159抗體
xy-9780R    C1orf1631號染色體開放閱讀框163抗體
xy-9781R    C1orf1721號染色體開放閱讀框172抗體
xy-9782R    C1orf21號染色體開放閱讀框2抗體
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xy-9786R    C1orf511號染色體開放閱讀框51抗體
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