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唾液酸轉(zhuǎn)移酶4A抗體

英文名稱 SIAT4A
中文名稱 唾液酸轉(zhuǎn)移酶4A抗體
別    名 3-GalNAc-alpha-2; 3-sialyltransferase 1; 3-sialyltransferase; 3-ST 1; Alpha 2; Alpha 23 ST; Beta galactoside alpha 23 sialyltransferase; Beta-galactoside alpha-2; beta-galactoside alpha-2,3-sialyltransferase 1; CMP N acetylneuraminate beta galactosamide alpha 23 sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2; DKFZp666E036; DKFZp779K2051; FLJ36548; Gal beta 13 GalNAc alpha 23 sialyltransferase; Gal NAc6S; Gal-beta-1; Gal-NAc6S; MGC9183; OTTHUMP00000226912; OTTHUMP00000226913; SIA4A_HUMAN; Sialyltransferase 4A; SIAT4-A; SIAT4A; SIATFL; ST3Gal I; ST3GAL1; ST3GalA; ST3GalA.1; ST3GalI; ST3GalIA; ST3O.

說(shuō) 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIAT4A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]

Function:
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.

Subcellular Location:
Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Tissue Specificity:
Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney, pancreas, spleen and placenta.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the glycosyltransferase 29 family.

Gene ID:
6482xy-0652R    Connexin-45間隙連接蛋白45抗體
xy-1009R    CXCR1細(xì)胞表面趨化因子受體1抗體
xy-0461R    CYP450細(xì)胞色素P450單氧化酶抗體
xy-0013R    Cytochrome C細(xì)胞色素C抗體
xy-1244R    CK1細(xì)胞角蛋白1抗體
xy-0271R    Cytomegalovirus pp65 巨細(xì)胞病毒PP65/CMV低基質(zhì)磷脂蛋白抗體
xy-0282R    Cyclin C周期素C抗體
xy-0572R    Cyclin B1周期素B1抗體
xy-0590R    Cytoglobin細(xì)胞球蛋白抗體
xy-0623R    Cyclin D1周期素D1抗體
xy-1148R    Cyclin D2周期素D2抗體
xy-0573R    Cyclin E周期素E抗體
xy-2521R    CD94/KLRD1NK細(xì)胞表面抑制性受體CD94抗體
xy-2498R    CD58淋巴細(xì)胞功能相關(guān)抗原-3抗體
xy-2484R    CCL27/CTACK皮膚T細(xì)胞虜獲趨化因子抗體
xy-4872R    Complement C3補(bǔ)體C3a過敏毒素抗體
xy-2477R    Macrophage Inflammatory Protein 1 gamma巨噬細(xì)胞炎癥蛋白-1γ抗體
xy-1996R    CD171神經(jīng)細(xì)胞粘附分子配體1抗體
xy-15284R    C8orf30A8號(hào)染色體開放閱讀框30a抗體
xy-3608R    CYP11A1細(xì)胞色素P450 11A1抗體
xy-2047R    CPT1A肉毒堿棕櫚?；D(zhuǎn)移酶1A抗體
xy-3555R    CDC42細(xì)胞分化周期CDC42蛋白抗體
xy-3369R    Phospho-CDC42 (Ser71)磷酸化細(xì)胞分化周期CDC42蛋白抗體
xy-1616R    CAP2環(huán)化酶相關(guān)蛋白CAP-2抗體
xy-1702R    CD15階段特異性胚胎表面抗原-1抗體
xy-15105R    C20orf20220號(hào)染色體開放閱讀框202抗體
xy-1474R    CCL28粘膜相關(guān)上皮趨化因子28抗體
xym-1623M    CEA(C3)癌胚抗原單克隆抗體（包被）
xym-1624M    CEA(B5)癌胚抗原單克隆抗體（檢測(cè)）
xy-1703R    Raf1癌基因c-Raf抗體
xy-0948R    Collagen IIIⅢ型膠原蛋白/膠原蛋白3/3型膠原蛋白抗體
xy-1523R    CD63黑色素瘤相關(guān)抗原抗體
xy-1514R    CD33CD33抗體
xy-1516R    CNTF Receptor alpha睫狀神經(jīng)營(yíng)養(yǎng)因子受體α抗體
xy-1520R    CD7CD7抗體
xy-1620R    CDX2尾型同源盒轉(zhuǎn)錄因子2抗體
xy-1432R    CD68CD68抗體
xy-1428R    Claudin 1緊密連接蛋白1抗體
xy-1539R    CD46膜輔蛋白抗體