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SIDT2蛋白抗體

英文名稱 SIDT2
中文名稱 SIDT2蛋白抗體
別    名 SIDT-2; B930096O19; BC023957; CGI 40; DKFZp686L17253; FLJ90656; MGC36407; MGC58967; RGD1308311; SID1 transmembrane family member 2; SID1 transmembrane family, member 2; SIDT2; SIDT2_HUMAN.
 
說(shuō) 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  通道蛋白  跨膜蛋白  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 94kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIDT2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

Subcellular Location:
Lysosome membrane.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the SID1 family.

Database links:

Entrez Gene: 51092 Human

Entrez Gene: 214597 Mouse

Entrez Gene: 315617 Rat

SwissProt: Q8NBJ9 Human

SwissProt: Q8CIF6 Mouse

SwissProt: D3ZEH5 Rat

Unigene: 712144 Human

Unigene: 379345 Mouse

Unigene: 162997 Rat

Important Note:
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xy-13820R    Phospho-CEBP beta (Thr188 + Thr235)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子CEBP β抗體
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xy-13822R    CEBPE轉(zhuǎn)錄調(diào)節(jié)因子C/EBPε抗體
xy-13823R    phospho-CEBPE (Thr74)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子C/EBPε抗體
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