干細胞生長因子SCGF抗體 返回列表頁

干細胞生長因子SCGF抗體

英文名稱 SCGF
中文名稱 干細胞生長因子SCGF抗體
別    名 SCGF beta; C type lectin domain family 11 member A; C type lectin superfamily member 3; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; CLC11_HUMAN; CLEC11A; CLECSF3; LSLCL; Lymphocyte secreted C type lectin; Lymphocyte secreted C-type lectin; lymphocyte secreted long form of C type lectin; p47; Stem cell growth factor; stem cell growth factor lymphocyte secreted C type lectin.
  
說 明 書 0.2ml  
研究領域 細胞生物  干細胞  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
細胞定位 細胞漿 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCGF
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SCGF is a cytokine for primitive hematopoietic progenitor cells and exhibits species-specific activity. It is predominantly expressed in proliferating chondrocytes, bone marrow cells, the periosteum and the perichondrium of skeletal tissues. SCGF contains an N-terminal Arg-Gly-Asp triplet (RGD triplet), leucine zipper domains, a C-terminal C-type lectin domain and numerous potential glycosylation sites. It has burst-promoting activity and granulocyte/macrophage colony-promoting activity in vitro. SCGF is directly correlated to granulocyte recovery following stem cell transplantation and thus can be an indicator of hematopoietic recovery following stem cell transplantation.

Function:
Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.

Subcellular Location:
Cytoplasm. Secreted.

Tissue Specificity:
Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.

Post-translational modifications:
O-glycosylated. Probably sulfated on the O-glycans.

Similarity:
Contains 1 C-type lectin domain.

Gene ID:
6320xy-10021R    CIAS1細胞凋亡誘導蛋白NALP3抗體
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xy-10059R    Cullin 5血管加壓素激活鈣啟動受體蛋白1抗體
xy-10005R    c-Kit干細胞生長因子受體/細胞表面分化抗原抗體
xy-12038R    CLIC6氯離子通道蛋白6抗體
xy-13825R    Cecropin B殺菌肽B/天蠶抗菌肽B抗體
xy-7981R    CA13碳酸酐酶13抗體
xy-10307R    Chloride Channel 5氯離子通道蛋白5抗體
xy-11636R    Contactin 4 + 6軸突相關粘附分子抗體
xy-13886R    CHCHD1卷曲螺旋結(jié)構(gòu)域蛋白CHCHD1抗體
xy-8162R    CHD3ATP依賴的解旋酶CHD3抗體
xy-7984R    CA7碳酸酐酶7抗體
xy-7985R    CCBE1膠原蛋白和鈣結(jié)合表皮生長因子結(jié)構(gòu)域1抗體
xy-7986R    CCDC102B卷曲螺旋結(jié)構(gòu)域蛋白102B抗體
xy-7987R    CCDC16卷曲螺旋結(jié)構(gòu)域蛋白16抗體
xy-8297R    CYBR1細胞色素B還原酶1抗體
xy-15160R    C2orf762號染色體開放閱讀框76抗體
xy-15166R    C3orf193號染色體開放閱讀框19抗體
xy-8166R    COX5A細胞色素c氧化酶5A抗體
xy-8093R    CCDC60卷曲螺旋結(jié)構(gòu)域蛋白60抗體
xy-8092R    CCDC144A卷曲螺旋結(jié)構(gòu)域蛋白144A抗體
xy-7884R    Cyclin B3周期素B3抗體
xy-8342R    CPXM2羧肽酶X(M14家族2)抗體
xy-8386R    Ecadherin binding protein E7上皮鈣粘附分子結(jié)合蛋白E7
xy-7885R    CCNDBP1周期素D結(jié)合蛋白1抗體
xy-8088R    CCDC120卷曲螺旋結(jié)構(gòu)域蛋白120抗體
xy-8089R    CCDC23卷曲螺旋結(jié)構(gòu)域蛋白23抗體
xy-8094R    CCDC89卷曲螺旋結(jié)構(gòu)域蛋白89抗體
xy-8097R    CCDC30卷曲螺旋結(jié)構(gòu)域蛋白30抗體
xy-8091R    CCDC40卷曲螺旋結(jié)構(gòu)域蛋白40抗體
xy-8095R    CCDC114卷曲螺旋結(jié)構(gòu)域蛋白114抗體