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電壓門控鈉離子通道型α4抗體

參   考   價: 10

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

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所  在  地上海

更新時間:2015-06-12 09:57:37瀏覽次數(shù):521次

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電壓門控鈉離子通道型α4抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.

電壓門控鈉離子通道型α4抗體

英文名稱 SCN4A
中文名稱 電壓門控鈉離子通道型α4抗體
別    名 HYKPP; HYPP; Na(V)1.4; NAC1A; Nav1.4; Scn4a; SCN4A_HUMAN; Skeletal muscle voltage dependent sodium channel type IV alpha subunit; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type 4 subunit alpha; Sodium channel protein type IV subunit alpha; Sodium channel voltage gated type IV alpha subunit; Voltage gated sodium channel subunit alpha Nav1.4; Voltage gated sodium channel type 4 alpha; Voltage-gated sodium channel subunit alpha Nav1.4.

說 明 書 0.2ml  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  通道蛋白  跨膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 208kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCN4A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生 產(chǎn) 商 BIOSS
PubMed PubMed
產(chǎn)品介紹 background:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]

Function:
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.

Subcellular Location:
Membrane.
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