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SCAPER蛋白抗體

英文名稱 SCAPER
中文名稱 SCAPER蛋白抗體
別    名 FLJ31533; FLJ31953; FLJ46212; KIAA1454; MSTP063; S phase cyclin A-associated protein in the endoplasmic reticulum; S phase cyclin A-associated protein in the ER; SCAPE_HUMAN; SCAPER; Zfp291; Zinc finger protein 291; ZNF291.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 158kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCAPER
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SCAPER is a 1,399 amino acid protein that contains a C2H2-type zinc finger, a putative transmembrane domain, an ER retrieval signal at the C terminus, four coiled-coil domains, six potential RXL motifs that might confer binding to cyclins and six consensus Cdk phosphorylation sites. SCAPER interacts with, and is phosphorylated in vitro by, the cyclin A/Cdk2 complex at multiple phases of the cell cycle, including S and G2/M. It has been suggested that SCAPER represents a novel cyclin A/Cdk2 regulatory protein that transiently maintains cyclin A in the cytoplasm. The SCAPER protein is predominantly located in the endoplasmic reticulum, with only a small portion detected in the nucleus. Widely expressed, SCAPER demonstrates highest expression in testis. Existing as two alternatively spliced isoforms, the SCAPER gene is conserved in chimpanzee, dog, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q24.3.

Function:
CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm.

Subcellular Location:
Endoplasmic reticulum. Nucleus. Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus.

Tissue Specificity:
Widely expressed with highest expression in testis.xy-5025R    Claudin 14緊密連接蛋白14抗體
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xy-3062R    Phospho-CEBP beta (Ser105)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子CEBP β抗體
xy-3063R    Phospho-CEBP beta (Thr235)磷酸化轉(zhuǎn)錄調(diào)節(jié)因子CEBP β抗體
xy-3264R    Phospho-CD18 (Ser756 + Thr758 + Thr759)磷酸化整合素β2/Integrin β2抗體
xy-3065R    Phospho-CD19 (Tyr531)磷酸化CD19抗體
xy-2753R    CENPA著絲粒蛋白A
xy-3066R    Phospho-CENPA (Ser7)磷酸化著絲粒蛋白A
xy-3068R    Phospho-CRMP2 (Thr514)磷酸化二氫嘧啶酶樣2抗體
xy-1487R    CC16克拉拉細(xì)胞蛋白抗體
xy-1481R    CD22B淋巴細(xì)胞粘附分子CD22抗體
xy-1598R    Cathepsin G組織蛋白酶G抗體
xy-1479R    CD80刺激分子B7-1蛋白抗體
xy-15023R    C1orf1451號(hào)染色體開(kāi)放閱讀框145抗體
xy-15102R    C20orf18620號(hào)染色體開(kāi)放閱讀框186抗體
xy-1610R    CK7細(xì)胞角蛋白7抗體
xy-1715R    Connexin 26間隙連接蛋白26抗體
xy-1529R    CD46/MCP膜輔蛋白抗體
xy-5161R    CAPZA1F肌動(dòng)蛋白α1亞基抗體
xy-4790R    CD8CD8抗體
xy-4791R    CD8 alphaCD8抗體
xy-4836R    CXCR2細(xì)胞表面趨化因子受體2抗體
xy-5158R    Cystatin B胱抑素B/半胱氨酸蛋白酶抑制劑B抗體
xy-2394R    CKLF趨化素樣蛋白抗體
xy-1588R    CK20細(xì)胞角蛋白20抗體
xy-1599R    Calpain 2鈣激活的中性蛋白酶2抗體
xy-1708R    CD45ROCD45RO抗體
xy-1482R    CD177嗜中性粒細(xì)胞抗原CD177抗體
xy-1682R    CIB1鈣整合素結(jié)合蛋白1抗體
xy-15128R    C21orf7 21號(hào)染色體開(kāi)放閱讀框7抗體