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清道夫受體A亞型5抗體

英文名稱 SCARA5
中文名稱 清道夫受體A亞型5抗體
別    名 FLJ23907; MGC45780; NET33; SCAR5_HUMAN; SCARA 5; scara5; Scavenger receptor class A member 5; Scavenger receptor class A, member 5 (putative); Scavenger receptor class A, member 5; Scavenger receptor hlg; Tesr; Testis expressed scavenger receptor.
    
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SCARA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SCARA5 is a 495 amino acid cell membrane protein. SCARA5 is expressed at high levels in testis, with highest levels specifically found in specific populations of epithelial cells and Sertoli cells. SCARA5 forms a homotrimer single-pass type II membrane complex present on the surface of the plasma membrane. Cells transfected with SCARA5 were able to bind particular gram-positive and gram-negative bacteria, suggesting a possible role for SCARA5 in immunity to infection. It has also been suggested that SCARA5 may be involved in transferrin delivery pathways. Expressed as four isoforms produced by alternative splicing, SCARA5 contains one collagen-like domain and one SRCR domain.

Function:
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).

Subunit:
Homotrimer. 

Subcellular Location:
Cell membrane.

Similarity:
Belongs to the SCARA5 family.
Contains 1 collagen-like domain. Contains 1 SRCR domain.

Gene ID:
286133xy-9805R    C2orf182號(hào)染色體開放閱讀框18抗體
xy-12925R    COX6c細(xì)胞色素c氧化酶6抗體
xy-2483R    CCL24嗜酸粒細(xì)胞趨化蛋白24抗體
xy-2480R    CCL15巨噬細(xì)胞炎性蛋白15
xy-2482R    CCL23/MIP3巨噬細(xì)胞炎性蛋白抗體
xy-2517R    CD72/Ly-32CD72蛋白抗體
xy-9306R    CEP128中心體蛋白128抗體
xy-9305R    CENPO著絲粒蛋白O抗體
xy-9824R    C3orf173號(hào)染色體開放閱讀框17抗體
xy-6310R    Caveolin-2細(xì)胞質(zhì)膜微囊蛋白-2抗體
xy-7523R    phospho-Caveolin-2(Tyr19)磷酸化細(xì)胞質(zhì)膜微囊蛋白-2抗體
xy-9822R    C3orf243號(hào)染色體開放閱讀框24抗體
xy-4871R    Complement C3 beta chain補(bǔ)體C3b抗體
xy-4873R    Complement C3b alpha' chain補(bǔ)體C3b-α鏈抗體
xy-4816R    CD3ECD3抗體
xy-15555R    CENPC1著絲粒蛋白C1抗體
xy-9128R    CDCA7細(xì)胞分裂周期相關(guān)蛋白
xy-4745R    CSFV豬瘟病毒抗體
xy-7341R    C16orf7216號(hào)染色體開放閱讀框72抗體
xy-10454R    Complement C4 gamma chain補(bǔ)體C4 γ 鏈蛋白抗體
xy-10453R    C4d-A補(bǔ)體C4d-A蛋白抗體
xy-10452R    C4b-A補(bǔ)體C4b-A蛋白抗體
xy-10462R    Phospho-CD18 (Thr758)磷酸化整合素β2/Integrin β2抗體
xy-10461R    Phospho-CD18 (Ser756)磷酸化整合素β2/Integrin β2抗體
xy-15189R    C4orf284號(hào)染色體開放閱讀框28抗體
xy-10473R    CATSPER2陽(yáng)離子通道精子相關(guān)蛋白2抗體
xy-7136R    CATSPER3陽(yáng)離子通道精子相關(guān)蛋白3抗體
xy-13922R    Chorein/VPS13A液泡蛋白分選蛋白VPS13A抗體
xy-13923R    Chp2鈣調(diào)磷酸酶B相關(guān)蛋白2抗體
xy-13924R    CHRAC1CHRAC1蛋白抗體
xy-13926R    CHD9ATP依賴的解螺旋酶抗體
xy-13927R    CXorf6X染色體開放閱讀框6抗體
xy-13928R    CHSS2硫酸軟骨素酶2抗體
xy-13929R    CHST10碳水化合物磺基轉(zhuǎn)移酶10抗體