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轉錄因子SOX18抗體
英文名稱 SOX18
中文名稱 轉錄因子SOX18抗體
別 名 HLTS; SOX 18; Sox18; SOX18_HUMAN; SRY (sex determining region Y) box 18; SRY box 18; Transcription factor SOX 18; Transcription factor SOX-18.
說 明 書 0.1ml 0.2ml
研究領域 發(fā)育生物學 轉錄調節(jié)因子 表觀遺傳學
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Rhesus monkey
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細胞定位 細胞核
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOX18
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-angiectasia. [provided by RefSeq, Jul 2008]
Function:
Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.
Subcellular Location:
Nucleus.
DISEASE:
Defects in SOX18 are the cause of hypotrichosis-lymphedema-angiectasia syndrome (HLTS) [MIM:607823].
Similarity:
Contains 1 HMG box DNA-binding domain.
Contains 1 Sox C-terminal domain.
Gene ID:
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xy-13110R ETFDH電子轉移黃素蛋白脫氫酶抗體
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xy-13112R ETNK2乙醇胺激酶2抗體
xy-13113R phospho-ETS1 (Thr38)磷酸化Ets轉錄因子家族ets1抗體
xy-10317R phospho-ECT2 (Ser370)磷酸化上皮細胞癌轉化蛋白2抗體
xy-3881R EPX嗜酸性粒細胞過氧化物酶抗體
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xy-3019R phospho-eIF4EBP1 (Thr37 + Thr46)磷酸化4E結合蛋白1抗體
xy-3016R phospho-ERK1/2 (Thr202 + Tyr204)磷酸化絲裂原活化蛋白激酶1/2抗體
xy-2305R E2EPF泛素交聯(lián)酶抗體
xy-4698R EBNA 3BEB病毒核抗原-3B抗體
xy-8179R phospho-Eg5(Thr926)磷酸化驅動蛋白樣蛋白1抗體
xy-6138R EID1乙?;D移酶EID1抗體
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xy-2913R EIF5真核翻譯起始因子5抗體
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