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突觸17抗體

英文名稱 STX17
中文名稱 突觸17抗體
別    名 FLJ20651; MGC102796; MGC126613; MGC126615; Stx17; STX17_HUMAN; Syntaxin 17; Syntaxin-17.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  免疫學  神經(jīng)生物學  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STX17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 17, also known as STX17, is a 302 amino acid single-pass type IV membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the syntaxin family. Thought to localize to the endoplasmic reticulum, Syntaxin 17 plays a role in vesicle trafficking to lysosomes and may be involved in processes related to cell division. The gene encoding Syntaxin 17 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic angiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Function:
Implicated in vesicle trafficking to lysosomes. Could be involved in processes related to cell division.

Subcellular Location:
Membrane. Appears to be associated with a membrane compartment, perhaps a subset of the ER such as exit or entrance sites.

Similarity:
Belongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain.

Gene ID:
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xy-12333R    ERMAP紅細胞膜相關(guān)蛋白ERMAP抗體
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xym-2279M    EMC1腺樣癌特異性相關(guān)抗原EMC1抗體
xy-12360R    Epiphycan硫酸軟骨素蛋白多糖3抗體
xy-10151R    Exportin 1/CRM1染色體區(qū)域穩(wěn)定蛋白/核輸出蛋白1抗體
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xy-12341R    ETV2ETS相關(guān)蛋白71抗體
xy-12347R    EDA外胚層發(fā)育不良蛋白1抗體
xy-13114R    ETV3LETV3L蛋白抗體
xy-2571R    EphB6酪氨酸蛋白激酶受體B6抗體
xy-2880R    LPA1溶血磷脂酸受體蛋白1抗體
xy-2881R    LPA2溶血磷脂酸受體蛋白2抗體
xy-2882R    LPA3溶血磷脂酸受體蛋白3抗體
xy-2883R    EDG6內(nèi)皮細胞的分化蛋白6抗體
xy-6005R    EXTL2外生性骨疣樣蛋白2抗體
xy-5334R    phospho-EIF4EBP1 (Ser100)磷酸化eIF4E結(jié)合蛋白抗體
xy-5337R    phospho-EIF4EBP1(Ser111)磷酸化eIF4E結(jié)合蛋白抗體
xy-3615R    ESM1內(nèi)皮細胞特異性分子1抗體
xy-3841R    eIF3F真核翻譯起始因子3F抗體
xy-3842R    eIF3H真核翻譯起始因子3H抗體
xy-3843R    eIF4G真核翻譯起始因子4G抗體
xy-3844R    eIF6β4整合素結(jié)合蛋白抗體
xy-9807R    ECRG4食道癌相關(guān)基因4蛋白抗體