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特異性雄激素調(diào)節(jié)蛋白抗體

英文名稱 SARG
中文名稱 特異性雄激素調(diào)節(jié)蛋白抗體
別    名 SARG; C1orf116; Chromosome 1 open reading frame 116; DKFZp666H2010; FLJ36507; MGC2742; MGC4309; OTTHUMP00000034747; Specifically androgen regulated gene protein; Specifically androgen regulated protein.
  
說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig, Cat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SARG
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf116 gene product has been provisionally designated C1orf116 pending further characterization.

Function:
C1orf116 belongs to the SARG family. It is a putative androgen-specific receptor. It is highly expressed in prostate.

Subcellular Location:
Cytoplasmicxy-2343R    EPO紅細胞生成素抗體
xy-3880R    EPHX2胞漿環(huán)氧化物水解酶抗體
xy-6213R    Estrogen Related Receptor gamma雌激素受體相關(guān)蛋白3抗體
xy-6212R    Estrogen Related Receptor beta雌激素相關(guān)受體β抗體
xy-6264R    EMP2上皮細胞膜蛋白2抗體
xy-2947R    ERG25甲基固醇羥化酶單加氧酶1抗體
xy-6527R    EST1A端粒酶結(jié)合蛋白EST1A抗體
xy-6528R    EZH1組蛋白賴氨酸N-甲基EZH1抗體
xy-6532R    Epithelial Stromal Interaction 1上皮間質(zhì)相互作用蛋白1抗體
xy-6533R    EIG121雌激素誘導(dǎo)基因121蛋白抗體
xy-5884R    Endomucin內(nèi)皮粘蛋白EMCN抗體
xy-5883R    EBP50細胞骨架連接質(zhì)膜蛋白抗體
xy-5807R    ELMO1吞噬細胞運動蛋白1抗體
xy-6636R    EPHA10酪氨酸蛋白激酶受體A10抗體
xy-2339R    EV71 polyprotein 3D腸道病毒71型/手足口病病毒抗體
xy-7042R    ELF1轉(zhuǎn)錄因子ELF1抗體
xy-7043R    Ephrin B3酪氨酸蛋白激酶B3抗體
xy-7044R    phospho-EphB1+EphB2 (Tyr594)磷酸化酪氨酸蛋白激酶受體B1+B2抗體
xy-7045R    EphB1+EphB2+EphB3+EphB4酪氨酸蛋白激酶受體B1+B2+B3+B4抗體
xy-11551R    EMX2空通氣孔樣蛋白2抗體
xy-11552R    EN2同源盒蛋白轉(zhuǎn)錄因子EN2抗體
xy-11553R    phospho-ERK5 (Thr218 + Tyr220)磷酸化細胞外信號調(diào)節(jié)激酶5抗體
xy-11515R    ENTPD2CD39樣蛋白1抗體
xy-10035R    EIF5真核翻譯起始因子5抗體
xy-11740R    EBF2早期B淋巴細胞因子2抗體
xy-11741R    ELAVL2ELAVL2蛋白抗體
xy-11743R    ELAVL2 + ELAVL4ELAVL2+ELAVL4蛋白抗體
xy-11744R    Engrailed 1同源盒蛋白轉(zhuǎn)錄因子EN1抗體
xy-11745R    ER81轉(zhuǎn)錄因子ER81蛋白抗體
xy-12560R    EAA1谷氨酸受體KA1抗體
xy-12057R    eIF3K真核翻譯起始因子3K抗體