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平滑肌蛋白抗體

英文名稱 Smoothelin
中文名稱 平滑肌蛋白抗體
別    名 FLJ35168; FLJ35365; FLJ35620; FLJ38597; Smoothelin; SMSMO; Smtn; SMTN_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  細胞類型標志物  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Orangutan
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Smoothelin
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The cytoskeletal protein smoothelin is highly conserved among vertebrates and is expressed exclusively by contractile smooth muscle cells where it localizes to the filament network. Smoothelin associates with actin stress fibers but does not interact with desmin. At least two isoforms of smoothelin are produced by alternative splicing. The short isoform lacks amino acids 1–544 at the amino-terminus of the long isoform. The short isoform is expressed in visceral muscle tissue, including intestine and stomach, but not in brain, while the long isoform is expressed in all vascularized organs. In the vascular system, smoothelin expression is limited to large veins and arteries capable of pulsatile contraction. As a marker for the highly differentiated contractile smooth muscle cell, smoothelin expression is useful for studying vascular malformation and injury. The gene encoding human smoothelin maps to chromosome 22q12.2.

Function:
Structural protein of the cytoskeleton.

Subcellular Location:
Cytoplasm > cytoskeleton. Exhibits a filamentous organization.

Tissue Specificity:
Smooth muscle; contractile or vascular (for the long form).xy-13246R    G gamma7G蛋白偶聯(lián)受體γ7抗體
xy-13247R    G protein alpha 13G蛋白結(jié)合蛋白α13/Gα13抗體
xy-13248R    G protein alpha 16G蛋白結(jié)合蛋白α16/Gα16抗體
xy-13249R    G protein alpha inhibitor 1G蛋白α抑制劑抗體
xy-13250R    G Protein alpha x+zG蛋白受體α x+z抗體
xy-13251R    GALC/Galactosylceramidase半乳糖神經(jīng)酰胺酶抗體
xy-10373R    Phospho-Glycogen synthase 1(Ser640)磷酸化葡萄糖合成酶1抗體
xy-10377R    Galectin-3半乳糖凝集素3抗體
xy-13642R    GRB7生長因子受體結(jié)合蛋白7抗體
xy-13377R    GLT1D1糖基轉(zhuǎn)移酶1結(jié)構(gòu)域1抗體
xy-15368R    GPCR LGR7G蛋白偶聯(lián)受體LGR7蛋白抗體
xy-15370R    GPCR MRGX2 G蛋白偶聯(lián)受體MRGX2蛋白抗體
xy-15371R    GPCR RDC1G蛋白偶聯(lián)受體RDC1蛋白抗體
xy-15373R    GPCR TAS1R1G蛋白偶聯(lián)受體TAS1R1蛋白抗體
xy-15374R    GPCR TGR7G蛋白偶聯(lián)受體TGR7蛋白抗體
xy-15381R    GPR157G蛋白偶聯(lián)受體GPR157蛋白抗體
xy-15387R    GPR176G蛋白偶聯(lián)受體GPR176蛋白抗體
xy-15354R    GPR10 G蛋白偶聯(lián)受體GPR10蛋白抗體
xy-15352R    GPCR C5L2 G蛋白偶聯(lián)受體C5L2蛋白抗體
xy-15353R    GPCR EX33 G蛋白偶聯(lián)受體EX33蛋白抗體
xy-15355R    GPR102 G蛋白偶聯(lián)受體GPR102蛋白抗體
xy-15390R    GPR37L1G蛋白偶聯(lián)受體GPR37樣蛋白1抗體
xy-15356R    GPR105 G蛋白偶聯(lián)受體GPR105蛋白抗體
xy-15358R    GPR12 G蛋白偶聯(lián)受體GPR12蛋白抗體
xy-15357R    GPR110 proteinG蛋白偶聯(lián)受體GPR110蛋白抗體
xy-15359R    GPR125 G蛋白偶聯(lián)受體GPR125蛋白抗體
xy-15372R    GPCR RTAG蛋白偶聯(lián)受體RTA蛋白抗體
xy-15380R    GPR155G蛋白偶聯(lián)受體GPR155蛋白抗體
xy-15360R    GPR30G蛋白偶聯(lián)受體GPR30蛋白抗體
xy-15365R    GPR86G蛋白偶聯(lián)受體GPR86蛋白抗體
xy-15367R    GPCR HM74G蛋白偶聯(lián)受體HM74蛋白抗體
xy-6892R    GMCL1L生殖細胞樣蛋白1樣蛋白抗體
xy-3178R    phospho-GAB2 (Tyr452)磷酸化接頭蛋白Gab 2抗體
xy-3182R    phospho-GAB2 (Tyr643)磷酸化接頭蛋白Gab2抗體
xy-3594R    GRIM19干擾素/維甲酸誘導凋亡相關(guān)基因抗體