可溶性E選擇素 返回列表頁

可溶性E選擇素

英文名稱 se-selectin
中文名稱 可溶性E選擇素
別    名 Endothelial leukocyte adhesion molecule 1; ELAM-1; Leukocyte-endothelial cell adhesion molecule 2; LECAM2; CD62 antigen-like family member E; CD62E antigen; LYAM2_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  細(xì)胞表面分子  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human se-selectin
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The se-selectin is expressed by cytokine-stimulated endothelial cells. It is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. This gene is present in single copy in the human genome and contains 14 exons spanning about 13 kb of DNA. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. 

Subunit:
Interacts with PSGL1/SELPLG through the sialyl Lewis X epitope. PSGL1 sulfation appears not to be required for this interaction.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains.xy-3183R    phospho-GAB2 (Ser623)磷酸化接頭蛋白Gab 2抗體
xy-13274R    GALNT13多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶13抗體
xy-13275R    gamma Adaptin銜接蛋白γ/γ1-Adaptin抗體
xy-13265R    GALE半乳糖瓦爾登轉(zhuǎn)化酶抗體
xy-13266R    Galectin 10半乳糖凝集素10抗體
xy-13267R    GALK2半乳糖激酶2抗體
xy-13268R    GALM半乳糖脫氫酶抗體
xy-13269R    GALNS硫酸軟骨素裂解酶抗體
xy-13270R    GALNT10多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶10抗體
xy-13271R    GALNT11多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶11抗體
xy-13272R    GALNT12多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶12抗體
xy-13273R    GALNT1多肽N-乙酰氨基半乳糖轉(zhuǎn)移酶1抗體
xy-13276R    gamma C Crystallin晶狀體球蛋白γ3/γC-crystallin/白內(nèi)障相關(guān)蛋白抗體
xy-13277R    GCP3γ-微管蛋白復(fù)合物GCP3抗體
xy-13278R    GAMT胍基乙酸N甲基轉(zhuǎn)移酶抗體
xy-13279R    GANCα-葡萄糖苷酶C抗體
xy-8867R    GHRHR生長激素釋放因子受體抗體
xy-13282R    GAPDHS3-磷酸甘油醛脫氫酶抗體
xy-13283R    GAPex5Rab5激活蛋白6抗體
xy-13290R    GAS41NuBI蛋白結(jié)合蛋白1抗體
xy-13291R    GSDMLGSDML蛋白抗體
xy-13293R    phospho-GATA2 (Ser401)磷酸化GATA結(jié)合蛋白2抗體
xy-13294R    phospho-GATA3 (Ser308)磷酸化GATA結(jié)合蛋白3抗體
xy-13295R    phospho-GATA4 (Ser105)磷酸化GATA結(jié)合蛋白4抗體
xy-13296R    GATMGATM蛋白抗體
xy-3766R    GARB1γ1氨基丁酸受體GABAA Rβ1抗體
xy-13499R    GPATCH2G蛋白修補(bǔ)結(jié)構(gòu)域蛋白2抗體
xy-3882R    GPX1谷胱甘肽過氧化酶1
xy-3790R    GM-CSF粒細(xì)胞-巨噬細(xì)胞克隆刺激因子抗體
xy-15361R    GPR62G蛋白偶聯(lián)受體GPR62蛋白抗體
xy-3854R    GREB1乳腺癌雌激素調(diào)控蛋白GREB1抗體
xy-4720R    GDF9生長分化因子9抗體
xy-2188R    GAPDH 3-磷酸甘油醛脫氫酶抗體
xy-3818R    GDF15生長分化因子15/巨嗜細(xì)胞抑制因子1抗體