肥大細(xì)胞蛋白酶7抗體 返回列表頁

肥大細(xì)胞蛋白酶7抗體

英文名稱 PRSS22
中文名稱 肥大細(xì)胞蛋白酶7抗體
別    名 Brain specific serine protease 4; BSSP 4; BSSP4; hBSSP 4; MGC9599; Prosemin; Protease serine 22; Protease serine S1 family member 22; PRSS 22; PRSS26; Serine protease 22; Serine protease 26; SP001LA; Tryptase epsilon.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRSS22
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a member of the trypsin family of serine proteases. The enzyme is expressed in the airways in a developmentally regulated manner. The gene is part of a cluster of serine protease genes on chromosome 16. [provided by RefSeq, Jul 2008]

Function:
Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA.

Subunit:
Homotetramer. The active tetramer is converted to inactive monomers at neutral and acidic pH in the absence of heparin. Low concentrations of inactive monomers become active monomers at pH 6.0 in the presence of heparin. When the concentration of active monomers is higher, they convert to active monomers and then to active tetramers. These monomers are active and functionally distinct from the tetrameric enzyme. In contrast to the hidden active sites in the tetrameric form, the active site of the monomeric form is accessible for macromolecular proteins and inhibitors eg: fibrinogen which is a substrate for the monomeric but not for the tetrameric form. The monomeric form forms a complex with SERPINB6.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland.

Similarity:
Belongs to the peptidase S1 family. Tryptase subfamily. 
Contains 1 peptidase S1 domain. xy-13535R    GPR40G蛋白偶聯(lián)受體40抗體
xy-13536R    GPR43G蛋白偶聯(lián)受體43抗體
xy-13537R    GPR44G蛋白偶聯(lián)受體44抗體
xy-13538R    GPR45G蛋白偶聯(lián)受體45抗體
xy-12352R    GSC同源盒蛋白GSC抗體
xy-13328R    Gemin 4脊髓性肌萎縮癥蛋白Gemin4抗體
xy-13329R    Gemin 5脊髓性肌萎縮癥蛋白Gemin5抗體
xy-13330R    Gemin 7脊髓性肌萎縮癥蛋白Gemin7抗體
xy-13331R    GEMGTP結(jié)合絲裂原誘導(dǎo)T細(xì)胞蛋白抗體
xy-13332R    GEMC1染色體卷曲螺旋域包含蛋白1抗體
xy-13333R    Gemin 6脊髓性肌萎縮癥蛋白Gemin6抗體
xy-13336R    phospho-GFAP (Ser38)磷酸化膠質(zhì)纖維酸性蛋白抗體
xy-13337R    GFI1自主生長(zhǎng)因子GFI1抗體
xy-10079R    GPR109AG蛋白偶聯(lián)受體109A抗體
xy-13343R    GGA1γ-銜接蛋白相關(guān)蛋白1抗體
xy-13344R    GGA2γ-銜接蛋白相關(guān)蛋白2抗體
xy-13345R    GGA3γ-銜接蛋白相關(guān)蛋白3抗體
xy-13347R    GGN配子生成素抗體
xy-13348R    GGT2 heavy chainγ谷氨酰轉(zhuǎn)肽酶2重鏈抗體
xy-13349R    GGT5 heavy chainγ-谷氨酰轉(zhuǎn)肽酶5重鏈抗體
xy-10279R    phospho-GATA3 (Ser115)磷酸化GATA結(jié)合蛋白3抗體
xy-10280R    phospho-GATA3 (Ser162)磷酸化GATA結(jié)合蛋白3抗體
xy-13339R    GFM2延伸因子G2抗體
xy-13383R    Glucoamylase葡糖淀粉酶抗體
xy-13341R    GFPT1谷氨酰胺6-磷酸果糖轉(zhuǎn)移酶抗體
xy-13400R    GSTT1谷胱甘肽S轉(zhuǎn)移酶θ抗體
xy-13441R    GSTT2谷胱甘肽S轉(zhuǎn)移酶θ2抗體
xy-13350R    GGT6γ-谷氨酰轉(zhuǎn)肽酶6抗體
xy-2578R    GZMA/Granzyme A顆粒酶A抗體
xy-2579R    Granzyme D/B/E/N/G/F/H顆粒酶D/B/E/N/G/F/H抗體
xy-2574R    G-CSFR/CD114/GCSF Receptor粒細(xì)胞-巨噬細(xì)胞集落刺激因子3受體抗體
xy-2575R    GPA/GYPA/CD235a血型糖蛋白A/涎糖蛋白抗體