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神經(jīng)突觸素12抗體

英文名稱 Syntaxin 12
中文名稱 神經(jīng)突觸素12抗體
別    名 MGC51957; Stx12; STX12_HUMAN; STX13; STX14; Syntaxin-12.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Syntaxin 12
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 12, also known as STX12, STX13 or STX14, is a 276 amino acid single-pass membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Syntaxin 12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I). Found in recycling endosomes, Syntaxin 12 colocalizes with transferrin receptor and is encoded by a gene located on human chromosome 1.

Function:
SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.

Subcellular Location:
Membrane. Golgi apparatus > trans-Golgi network membrane.

Similarity:
Belongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain.

Database links:

Entrez Gene: 100226 Mouse

Entrez Gene: 65033 Rat

SwissProt: Q9ER00 Mouse

Unigene: 28237 Mouse

Unigene: 54570 Ratxy-4062R    Glycerol kinase甘油激酶抗體
xy-4061R    GPD2線粒體甘油三磷酸脫氫酶2抗體
xy-4143R    Glutamine synthetase谷氨酰胺合成酶/谷氨酸氨連接酶抗體
xy-2388R    GPD1甘油三磷酸脫氫酶1抗體
xy-2367R    ganglioside GM1神經(jīng)節(jié)苷酯抗體
xy-5163R    GSTA3谷胱甘肽S轉(zhuǎn)移酶A3抗體
xy-5177R    phospho-GADD153 (Ser30)磷酸化GADD153抗體
xy-3939R    G protein alpha SG蛋白αS抗體（鳥嘌呤核苷酸結(jié)合蛋白Gα s）
xy-3940R    G protein beta 4G蛋白β4抗體/鳥嘌呤核苷酸結(jié)合蛋白β亞基4
xy-3942R    G protein beta 2G蛋白β2抗體/鳥嘌呤核苷酸結(jié)合蛋白β亞基2
xy-3944R    GNG2G蛋白γ2抗體/鳥嘌呤核苷酸結(jié)合蛋白γ2抗體
xy-4079R    phospho-GSK3 Beta (Tyr216)磷酸化糖原合酶激酶3β抗體
xy-15366R    GPR92G蛋白偶聯(lián)受體GPR92蛋白抗體
xy-6989R    G6PDH己糖6磷酸脫氫酶抗體
xy-13243R    G gamma14G蛋白偶聯(lián)受體γ14抗體
xy-4584R    GLP 2腸高血糖素相關(guān)肽抗體
xy-6325R    GLUT10葡萄糖轉(zhuǎn)運蛋白10抗體
xy-4585R    GRPP腸高血糖素相關(guān)肽抗體
xy-8596R    GPR120G蛋白偶聯(lián)受體120抗體
xy-9564R    GPR40G蛋白偶聯(lián)受體40抗體
xy-11402R    GCX1/C20orf10020號染色體開放閱讀框100抗體
xy-11403R    GNRHR2促性腺素釋放激素受體2抗體
xy-11404R    GPR106G蛋白偶聯(lián)受體106抗體
xy-8656R    G1switch 2G0/G1期開關(guān)調(diào)節(jié)蛋白2抗體
xy-15386R    GPR162G蛋白偶聯(lián)受體GPR162蛋白抗體
xy-11406R    GIOT1鋅指蛋白461抗體
xy-6880R    GPR109AG蛋白偶聯(lián)受體109A抗體
xy-13367R    GKAP1G激酶錨定蛋白1抗體
xy-13361R    GIYD2DNA修復(fù)蛋白GIYD2抗體
xy-6384R    GIDRP88生長抑制和分化相關(guān)蛋白抗體
xy-6383R    GANP生發(fā)中心相關(guān)核蛋白MCM3抗體
xy-4974R    Glucose 6 Phosphate Dehydrogenase葡萄糖-6磷酸脫氫酶抗體