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肝細(xì)胞生長(zhǎng)因子激活抑制蛋白2抗體

英文名稱 HGFA Inhibitor 2
中文名稱 肝細(xì)胞生長(zhǎng)因子激活抑制蛋白2抗體
別    名 Bikunin, placental; DIAR3; HAI-2; HAI2; Hepatocyte growth factor activator inhibitor type 2; Kop; Kunitz type protease inhibitor 2; Kunitz-type protease inhibitor 2; Kunitz-type serine protease inhibitor; PB; Placental bikunin; HGFA Inhibitor2; HGFA Inhibitor-2; Serine peptidase inhibitor Kunitz type 2; Serine protease inhibitor, Kunitz type, 2; SPINT2; SPIT2_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 發(fā)育生物學(xué)  神經(jīng)生物學(xué)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SPINT2/HAI2/HGFA Inhibitor 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
Tissue damage, such as hepatic and renal injury, initiates hepatocyte growth factor activator (HGFAC)-mediated limited proteolytic activation of the inactive single-chain precursor form of HGF. Initially, HGFAC is produced as a precursor protein, which is activated by limited proteolysis and is neutralized by specific inhibitors known as HGF activator inhibitors, designated HAIs. HAIs belong to the Kunitz-type serine protease inhibitor family. HAIs target HGF activator and are involved in the regulation of proteolytic activation of HGF in injured tissues. Human HAI-1 transcript is expressed in various human tissues, such as adult placenta, kidney, pancreas, prostate and small intestine, and fetal kidney and lung. It translates into a 478 amino acid protein. The human HAI-2 gene maps to chromosome 19q13.1 and encodes a 252 amino acid protein, also designated human placental bikunin or kop (Kunitz domain containing protein over-expressed in pancreatic cancer). HAI-1 and HAI-2 are produced in membrane-associated forms, which are secreted as active, proteolytically truncated proteins.

Function:
Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.

Subcellular Location:
Membrane; Single-pass type I membrane protein.xy-8379R    HIP2泛素蛋白連接酶E2抗體
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xy-11851R    HELT轉(zhuǎn)錄因子HELT蛋白抗體
xy-11852R    HES6轉(zhuǎn)錄因子HES6抗體
xy-11853R    HMX2同源盒蛋白H6亞型2抗體
xy-11854R    HS6ST1硫酸乙酰肝素6腦苷脂轉(zhuǎn)硫酸酶1抗體
xy-11646R    Humanin神經(jīng)保護(hù)肽HN抗體
xy-4646R    Capsid protein VP1大鼠細(xì)小病毒H-1株(H-1)抗體（N端）
xy-2946R    HAS1透明質(zhì)酸合成酶1抗體
xy-5898R    HIF3 alpha缺氧誘導(dǎo)因子3α/HIF-3α抗體
xy-5899R    HIFPH4缺氧誘導(dǎo)因子脯氨酰4羥化酶抗體
xy-5888R    Hyaluronidase2透明質(zhì)酸酶2/玻璃酸酶2抗體
xy-5822R    H Cadherin心臟鈣粘蛋白抗體
xy-6592R    HSD17B617-β-羥脫氫酶6抗體
xy-4813R    H5N1-H5禽流感H5亞型全病毒抗體
xy-2942R    ORF K14(HHV8)人類皰疹病毒8 ORF14抗體
xy-5889R    Hyaluronidase3透明質(zhì)酸酶2/玻璃酸酶2抗體
xy-6538R    HOXB2同源盒蛋白B2抗體
xy-6539R    HOXB8同源盒蛋白B8抗體
xy-6540R    HSPA6熱休克蛋白70家族蛋白6抗體
xy-9913R    HGFA肝細(xì)胞生長(zhǎng)因子激活蛋白抗體
xy-6537R    HDGF肝癌衍生生長(zhǎng)因子抗體（高遷移率族蛋白1樣蛋白2抗體）
xy-5386R    Phospho-Histone H3(Thr3)磷酸化組蛋白H3抗體
xy-9026R    HPRT次黃嘌呤磷酸核糖基轉(zhuǎn)移酶1抗體
xy-3776R    Histone H3 (acetyl K9)乙?；M蛋白H3抗體
xy-3748R    Acetyl and phospho-Histone H3 (Ac-K9/p-Ser10)乙?；土姿峄M蛋白H3抗體
xy-3779R    Histone H2A組蛋白H2A抗體
xy-3781R    Acetyl-Histone H2A(K5)乙?；M蛋白H2A抗體
xy-3782R    Acetyl-Histone H2B(K5)乙酰化組蛋白H2B抗體
xy-3783R    Acetyl-Histone H2B(K20)乙?；M蛋白H2B抗體