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G蛋白偶聯(lián)嘌呤受體p2y6抗體

英文名稱(chēng) P2Y6
中文名稱(chēng) G蛋白偶聯(lián)嘌呤受體p2y6抗體
別    名 G coupled nucleotide receptor; G protein coupled 6; MGC15335; P2 purinoceptor; P2RY6; P2RY6_HUMAN; P2Y purinoceptor 6; P2Y6; P2Y6 receptor; PP2891; Purinergic receptor P2Y6; pyrimidinergic receptor P2Y; Pyrimidinergic receptor P2Y, G protein coupled, 6.
   
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  通道蛋白  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2Y6
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. The P2Y receptors are differentially expressed in several tissue types, such as heart, lung and brain. However, all P2Y receptors are expressed in leukocytes, which suggests a role for the P2Y receptor family in the activation of leukocytes and plaets in response to inflammation or vascular damage.

Function:
Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.xy-1771R    IL-14/Taxilin alpha白介素14抗體
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xy-0047R    Insulin Receptor alpha胰島素受體α抗體
xy-1057R    Integrin Alpha 3 + Beta 1整合素α3β1抗體
xy-1051R    Integrin beta 7整合素β7抗體
xy-1109R    IQGAP1支架蛋白抗體
xy-0745R    IGC非洲爪蟾IGC抗體
xy-1031R    IFITM1干擾素誘導(dǎo)跨膜蛋白1抗體
xy-0784R    IFN-β干擾素β抗體
xym-0388M    IFN gamma(F2E4)γ-干擾素/γ-IFN單克隆抗體
xy-0481R    IFN gamma干擾素-γ/IFN-γ抗體
xy-0480R    IFN gamma干擾素-γ/IFN-γ抗體
xy-0227R    IGF1R胰島素樣生長(zhǎng)因子I受體抗體
xy-0680R    IGF1R胰島素樣生長(zhǎng)因子1受體抗體
xy-1108R    IGFBP2胰島素樣生長(zhǎng)因子結(jié)合蛋白2抗體
xy-0406R    IGFBP5胰島素樣生長(zhǎng)因子結(jié)合蛋白5抗體
xy-0014R    IGF 1胰島素樣生長(zhǎng)因子1抗體
xy-0015R    IGF II胰島素樣生長(zhǎng)因子-II抗體
xy-0698R    IL-10白細(xì)胞介素10抗體
xy-0560R    IL-13白介素13抗體
xy-1183R    IL-17白介素-17抗體
xy-0529R    IL-18白細(xì)胞介素-18/干擾素γ誘導(dǎo)因子抗體
xy-0445R    IL1RAPL1白介素1受體相關(guān)蛋白樣1前體蛋白抗體
xy-0812R    IL-1 Beta白介素1β/IL-1β抗體
xy-1191R    IL-2白介素2抗體（大、小鼠）
xym-0389M    IL-2(H2E4)白細(xì)胞介素-2單克隆抗體
xy-1193R    IL-23白介素-23抗體
xy-0581R    IL-4白介素4抗體
xy-0781R    IL-6白介素6
xy-0782R    IL-6白介素6抗體