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突觸富含脯氨酸膜蛋白7抗體

英文名稱 PRR7
中文名稱 突觸富含脯氨酸膜蛋白7抗體
別    名 Proline rich protein 7; Proline-rich protein 7; Prr7; PRR7_HUMAN; Synaptic proline rich membrane protein; Synaptic proline-rich membrane protein; transmembrane adaptor protein 3; TRAP3.

說 明 書 0.2ml  
研究領域 神經(jīng)生物學  信號轉(zhuǎn)導  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Sheep, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRR7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
PRR7 (proline rich 7), also known as Synaptic proline-rich membrane protein, is a 269 amino acid protein expressed in postsynaptic density (PSD) of the forebrain, especially in hippocampus. The proline rich sequence for which the protein is named is characteristic of a region that is involved in protein-protein interactions, acting as a ligand for SH3, WW and EVH1 domains. As a single-pass type III membrane protein, evidence shows that PRR7 forms a postsynaptic membrane complex with PSD-95 and NMDAz1, suggesting its possible function in the modulation of neural activities. The expression pattern in brain also suggests that PRR7 is essential for synaptic formation or maturation, specifically in the cerebrum. Two isoforms of PRR7 exist as a result of an alternative splicing event.

Subcellular Location:
Membrane. Cell junction > synapse > postsynaptic cell membrane. Enriched in post-synaptic plasma membrane and postsynaptic densities (PSD). Accumulates in spines along with synapse maturation and colocalizes with DLG4 in a punctate pattern.xy-5441R    phospho-IKK beta(S474)磷酸化KB抑制蛋白激酶β抗體
xy-5442R    phospho-IKK beta(Ser476)磷酸化KB抑制蛋白激酶β抗體
xy-5443R    phospho-ILK-1(Thr173)磷酸化整合素連接激酶1抗體
xy-5444R    phospho-ILK-1(Ser246) 磷酸化整合素連接激酶1抗體
xy-5445R    phospho-ILK-1(Ser259)磷酸化整合素連接激酶1抗體
xy-5446R    phospho-IRS1(Thr176)磷酸化胰島素受體底物1抗體
xy-5450R    phospho-ICAM1(Tyr512)磷酸化細胞間粘附分子1抗體
xy-5452R    phospho-ITGB3(Tyr785)磷酸化整合素β3抗體
xy-5447R    phospho-IGF1R (Tyr980)磷酸化胰島素樣生長因子1受體抗體
xy-5448R    phospho-IGF1R (Tyr1280)磷酸化胰島素樣生長因子1受體抗體
xy-5449R    phospho-IGF1R (Tyr1165 + Tyr1166)磷酸化胰島素樣生長因子1受體抗體
xy-5451R    phospho-ITGB3(Tyr773)磷酸化整合素β3抗體
xy-15574R    IGIP免疫球蛋白A誘導同源蛋白抗體
xy-4586R    IL-2白介素2抗體
xy-4586M    IL-2白介素2抗體
xy-6669R    ID4DNA結(jié)合抑制因子4抗體
xy-6670R    IGF2R胰島素樣生長因子2受體抗體
xy-2954R    IKZF3鋅指蛋白Aiolos抗體
xy-11586R    SOX13胰島細胞抗原12/核轉(zhuǎn)錄因子SOX13抗體
xy-7838R    INSC有絲分裂相關(guān)蛋白INSC抗體
xy-8583R    phospho-IKKi(Ser172)磷酸化核因子NFκB抑制蛋白激酶i抗體
xy-8590R    RanBP7RAN結(jié)合蛋白7抗體
xy-0411R    Rabbit Anti-IgG heavy chain constant region兔抗人γ-鏈
xy-15579R    IGSF9B免疫球蛋白超家族成員B抗體
xy-15580R    IHPK3六磷酸肌醇激酶3抗體
xy-15524R    IFNK干擾素kappa蛋白抗體
xy-4946R    IL-1 Alpha白介素1α/IL-1α抗體
xy-4947R    IL-1 Alpha白介素1α/IL-1α抗體
xy-11300R    phospho-IL2 Receptor beta (Tyr364)磷酸化白介素2受體β鏈抗體
xy-11301R    INSL3胰島素樣蛋白3抗體
xy-8680R    IRE1a內(nèi)質(zhì)網(wǎng)核信號轉(zhuǎn)導蛋白a1抗體
xy-4986R    rhIL-18重組人白細胞介素18抗體