鈣/鈣調(diào)素依賴蛋白激酶1β/CaMKIβ抗體 返回列表頁

鈣/鈣調(diào)素依賴蛋白激酶1β/CaMKIβ抗體

英文名稱 PNCK
中文名稱 鈣/鈣調(diào)素依賴蛋白激酶1β/CaMKIβ抗體
別    名 Calcium/calmodulin dependent protein kinase type 1B; Calcium/calmodulin-dependent protein kinase type 1B; CaM KI beta; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMK1b; CaMKI beta; CaMKI-beta; EC 2.7.11.17; KCC1B_HUMAN; MGC45419; PNCK; Pregnancy up regulated non ubiquitously expressed CaM kinase; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase.
   
說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, Sheep, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PNCK
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CaMKI Beta (Ca2+/calmodulin-dependent protein kinase type 1B), also known as PNCK (pregnancy up-regulated non-ubiquitously expressed CaM kinase) or BSTK3, is a 343 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. Existing as multiple alternatively spliced isoforms, CaMKI Beta functions to catalyze the ATP-dependent phosphorylation of CaMKI, an event that activates CaMKI activity and may be important for Ca2+-triggered signaling cascades within the cell. The gene encoding CaMKI Beta maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

Function:
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Phosphorylated by CAMKK1.xy-0734R    KGF纖維母細胞生長因子7抗體
xy-2772R    KLF2肺Kruppel樣因子抗體
xy-5869R    KLK5激肽釋放酶5抗體
xy-5866R    KLK13激肽釋放酶13抗體
xy-5867R    KLK15激肽釋放酶15抗體
xy-5868R    KLK2激肽釋放酶2抗體
xy-5865R    KLK12激肽釋放酶12抗體
xy-2501R    KiSS1 receptorG蛋白偶聯(lián)受體54抗體
xy-3527R    KIF17驅(qū)動蛋白家族KIF17抗體
xy-3644R    KLF9轉(zhuǎn)錄因子KLF9抗體
xy-2531R    NES/KLK10上皮細胞特異性蛋白1抗體
xy-5403R    phospho-KCNC1(Ser503)磷酸化離子通道蛋白Kv3.1抗體
xy-2812R    KAT4細胞周期基因1蛋白抗體
xy-2385R    KLF5驅(qū)動蛋白KIF5B抗體
xy-7752R    KLHL13kelch樣蛋白13抗體
xy-11569R    KCNN3鈣激活鉀通道蛋白3抗體
xy-11570R    KIBRA腎臟和腦蛋白抗體
xy-7751R    KIF2B有絲分裂驅(qū)動蛋白樣2B抗體
xy-7753R    KLHL9kelch樣蛋白9抗體
xy-7804R    KIF15驅(qū)動蛋白家族成員15抗體
xy-7808R    KNTC1著絲點關(guān)聯(lián)蛋白1抗體
xy-7806R    KLHDC5kelch樣蛋白5抗體
xy-7805R    KIFC1驅(qū)動蛋白家族成員C1抗體
xy-7807R    KLHL22Kelch樣蛋白22抗體
xy-6671R    KCND1電壓門控鉀通道Kv4.1抗體
xy-6674R    KCNK3酸敏感鉀離子通道蛋白3抗體
xy-2925R    KlothoKlotho多肽蛋白抗體
xy-6675R    KCNN4鈣激活鉀通道蛋白4抗體
xy-8049R    KLHL23Kelch樣蛋白23抗體
xy-8044R    KBTBD10BTB-kelch蛋白家族10抗體
xy-8045R    KBTBD4BTB-kelch蛋白家族4抗體
xy-8050R    KLHL24Kelch樣蛋白24抗體