多胺調(diào)制因子結(jié)合蛋白1抗體 返回列表頁

多胺調(diào)制因子結(jié)合蛋白1抗體

英文名稱 PMFBP1
中文名稱 多胺調(diào)制因子結(jié)合蛋白1抗體
別    名 PMF 1 binding protein; PMF-1-binding protein; PMFBP_HUMAN; Pmfbp1; Polyamine modulated factor 1 binding protein 1; Polyamine-modulated factor 1-binding protein 1.
  
說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 119kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from Human PMFBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
PMF-1 is a 205 amino acid protein involved in kinetochore formation. Localized to the nucleus, PMF-1 contains a coiled-coil domain which interacts with the leucine-zipper domain of Nrf2. This interaction regulates the transcription of SSAT, a regulatory enzyme for polyamine catabolism. PMF-1 is also a component of the MIS12 complex, which is required for kinetochore formation and chromosomal alignment and segregation. PMF-1 is expressed at highest levels in skeletal muscle and heart, with moderate expression in liver and kidney. PMFBP1 (Polyamine-modulated factor 1-binding protein 1) is a 1022 amino acid protein that binds PMF-1 and may be involved in general organization of the cytoskeleton. Due to evidence that PMFBP1 may play a role in sperm tail morphology, it may therefore affect fertility. There are three isoforms of PMFBP1 that are produced as a result of alternative splicing events. 

Function:
May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton.Target information above from: UniProt accession Q8TBY8 The UniProt Consortium The Universal Protein Resource (UniProt) in 2010 Nucleic Acids Res. 38:D142-D148 (2010). 

Database links:
UniProtKB/Swiss-Prot: Q8TBY8.1xy-1177R    Lingo-1Nogo受體反應(yīng)蛋白抗體
xy-0738R    Livin凋亡抑制蛋白抗體
xy-0821R    laminin層粘連蛋白抗體
xy-0759R    Lpin1 proteinLpin1 抗體
xy-0760R    Lpin1 proteinLpin1 抗體
xy-0816R    Lysozyme溶菌酶抗體
xy-0484R    Iumbrokinase蚓激酶抗體
xy-0409R    Leptin瘦素抗體
xy-0410R    Leptin receptor瘦素受體抗體
xy-0109M    Leptin receptor(long)瘦素受體抗體（長）
xy-9708R    LCE1A晚期包膜蛋白1抗體
xy-6862R    LANPL富含亮氨酸樣酸性核蛋白抗體
xy-9709R    LCE2B晚期包膜蛋白2B抗體
xy-9711R    LIPK脂肪酶家庭成員K抗體
xy-1902R    Stathmin白血病相關(guān)蛋白18/癌蛋白18抗體
xy-2035R    LIS1無腦回的致病基因LIS1抗體
xy-2556R    LAMP3溶酶體相關(guān)膜蛋白3抗體
xy-1758R    L-ENK亮氨酸腦啡肽抗體
xy-2912R    LC3B/MAP LC3β/MAP1A自噬微管相關(guān)蛋白輕鏈3抗體
xy-11780R    LMX1b指甲髕骨綜合征相關(guān)蛋白NPS1抗體
xy-4843R    LC3B自噬微管相關(guān)蛋白輕鏈β3抗體
xy-8361R    LRRC59LRRC59蛋白抗體
xy-8362R    LRRC41LRRC41蛋白抗體
xy-6431R    LHR促黃體生成素受體抗體
xy-11131R    alpha Lactalbumin乳清蛋白α抗體
xy-11132R    Lamin B2核纖層蛋白B2抗體
xy-1086R    Laminin alpha 5層粘蛋白α5抗體
xy-0619R    L-CitrullineL-瓜氨酸抗體
xy-9487R    LACE1泌乳升高蛋白1抗體
xy-9562R    LAPTM4A溶酶體相關(guān)膜蛋白4α抗體