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6-二磷酸酯酶1抗體

英文名稱 FBP1
中文名稱 6-二磷酸酯酶1抗體
別    名 6-bisphosphatase 1; 6-bisphosphate 1-phosphohydrolase 1; D fructose 1 6 bisphosphate 1 phosphohydrolase 1; D-fructose-1; EC 3.1.3.11; F16P1_HUMAN; FBP; FBP 1; FBPase 1; Fructose 1 6 bisphosphatase 1; Fructose bisphosphatase 1; Fructose-1; Growth inhibiting protein 17; Liver fructose bisphosphatase.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fructose-1,6-bisphosphatase 1 (2-100aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2), and ADP. Human PFK-1 is tetrameric and isoenzymes include, PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B), and PFK-1 plaet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, Inducible PFK-2) and PFK-2 testis (PFKFB4).

Subunit:
Homotetramer. 

Tissue Specificity:
Ubiquitous.

Similarity:
In the C-terminal section; belongs to the phosphoglycerate mutase family. 

Gene ID:
2203

Database links:

Entrez Gene: 2203 Human

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xy-4940R    Metallothionein 3金屬硫蛋白3抗體
xy-9109R    MAP4K6 絲裂原活化蛋白激酶MAP4K6抗體
xy-0266R    MAP65擬南芥MAP65蛋白抗體
xy-11201R    Musashi 1神經(jīng)干細(xì)胞RNA結(jié)合蛋白Musashi1抗體
xy-11179R    MAdCAM1粘膜細(xì)胞粘附分子1抗體
xy-4943R    MPO髓過氧化物酶抗體
xy-11352R    MAGI1膜相關(guān)鳥苷酸反轉(zhuǎn)激酶1抗體
xy-11353R    Munc13 神經(jīng)突觸前膜胞內(nèi)蛋白13抗體
xy-11322R    Membralin高度保守基因相關(guān)蛋白Membralin抗體
xy-11320R    MNX1運(yùn)動神經(jīng)元及胰腺同源蛋白1抗體
xy-11184R    MOBP少突膠質(zhì)細(xì)胞髓鞘相關(guān)蛋白抗體
xy-11189R    MRCK alphaCDC42結(jié)合蛋白激酶α抗體（MRCKα）
xy-1047R    MyD88髓樣分化蛋白抗體
xy-0337R    Myelin Protein Zero外周髓磷脂P0蛋白/P0蛋白抗體
xy-0027R    Melatonin Receptor 1A褪黑素受體1A/松果體素受體1A抗體
xy-3550R    Myogenin肌細(xì)胞生成素抗體
xy-3296R    Phospho-Myt1(Ser83)磷酸化髓鞘轉(zhuǎn)錄因子1抗體
xy-3503R    Mre11DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3293R    Phospho-Mre11 (Ser676)磷酸化DNA損傷關(guān)鍵蛋白Mre11抗體
xy-3504R    MST1蛋白激酶MST抗體
xy-3294R    Phospho-Mst1(Thr183) + Mst2(Thr180)磷酸化蛋白激酶MST抗體
xy-3295R    Phospho-MYL(Ser19)磷酸化肌球蛋白輕鏈2抗體
xy-3505R    Myt1髓鞘轉(zhuǎn)錄因子1抗體
xy-1352R    MCL1髓樣細(xì)胞白血病-1抗體
xy-1369R    MAP2微管相關(guān)蛋白2抗體
xy-9470R    MEF2B肌細(xì)胞增強(qiáng)因子2B抗體
xy-9471R    MESP1心血管發(fā)育中胚層相關(guān)蛋白1抗體
xy-9440R    MTA2轉(zhuǎn)移相關(guān)蛋白2抗體
xy-9375R    MYCBP2MYC結(jié)合蛋白2抗體
xy-9314R    MAP7D1精氨酸/脯氨酸富含卷曲蛋白1抗體