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神經(jīng)細(xì)胞突觸蛋白PCLO抗體

英文名稱 Piccolo
中文名稱 神經(jīng)細(xì)胞突觸蛋白PCLO抗體
別    名 ACZ; Aczonin; Brain-derived HLMN protein; DKFZp779G1236; KIAA0559; Multidomain presynaptic cytomatrix protein; PCLO; PCLO_HUMAN; Piccolo (presynaptic cytomatrix protein); Piccolo, mouse, homolog of antibody Pico; Presynaptic cytomatrix protein; Protein piccolo.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 557kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Piccolo
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Piccolo is 1 component of the presynaptic cytomatrix. Bassoon is a large protein which is also found in the presynaptic compartments of rat brain synapses. Bassoon, along with Piccolo, is part of the ensemble of presynaptic proteins that are involved in orchestrating events at the nerve terminal. Bassoon is found in axon terminals of hippocampal neurons where it is highly concentrated in the vicinity of the active zone. Piccolo has a similar distribution and colocalizes with Bassoon in cultured hippocampal cells. Piccolo zinc fingers interact with the dual prenylated rab3A and VAMP2/ Synaptobrevin II receptor PRA. Bassoon may be involved in cytomatrix organization at the site of neurotransmitter release. The gene which encodes bassoon maps to human chromosome 3p21.31. The gene which encodes piccolo maps to human chromosome 7q21.11.

Function:
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xy-1801R    NPTN間質(zhì)細(xì)胞衍化因子受體1抗體
xy-11918R    Neuro D2神經(jīng)細(xì)胞分化因子2抗體
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xy-11905R    NPAS3神經(jīng)細(xì)胞PAS結(jié)構(gòu)域蛋白3抗體
xy-11913R    NPDC1神經(jīng)細(xì)胞增殖和分化調(diào)控蛋白1抗體
xy-11914R    NRARPNOTCH調(diào)節(jié)錨蛋白抗體
xy-11915R    NRSN1神經(jīng)囊泡膜蛋白1抗體
xy-11916R    Neugrin突觸生長相關(guān)蛋白抗體
xy-8301R    NDUFA9NDUFA9蛋白抗體
xy-8363R    NIPA間變性淋巴瘤激酶核相互作用伴侶蛋白抗體
xy-8364R    phospho-NIPA(Ser354)磷酸化間變性淋巴瘤激酶核相互作用伴侶蛋白抗體
xy-7764R    NUSAP1核仁和紡錘體相關(guān)蛋白1抗體
xy-2054R    Nkx2.5心臟特異性同源盒轉(zhuǎn)錄因子NKX2.5抗體
xy-2975R    Noggin指(趾)關(guān)節(jié)粘連NOG蛋白抗體
xy-0700R    NSBP1核小體結(jié)合蛋白1抗體
xy-11036R    Neurexin 1軸突蛋白1(Neurexin 1α)抗體
xy-11105R    Ninjurin 1神經(jīng)損傷誘導(dǎo)蛋白1抗體
xy-11106R    Ninjurin 2神經(jīng)損傷誘導(dǎo)蛋白2抗體
xy-6261R    NEK3絲氨酸/蘇氨酸蛋白激酶Nek3抗體
xy-5732R    NEK2中心體相關(guān)蛋白激酶Nek2抗體
xy-11435R    Neurogranin神經(jīng)顆粒素抗體
xy-11428R    Neuropeptide S神經(jīng)肽S抗體
xy-11429R    Neuropeptide S神經(jīng)肽S抗體
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