先天性眼外肌纖維化相關(guān)蛋白FEOM2抗體 返回列表頁

先天性眼外肌纖維化相關(guān)蛋白FEOM2抗體

英文名稱 PHOX2A
中文名稱 先天性眼外肌纖維化相關(guān)蛋白FEOM2抗體
別    名 Aristaless homeobox (Drosophila) fibrosis of extraocular muscles congenital 2 autosomal recessive; Aristaless homeobox gene homolog (Drosophila); Aristaless homeobox homolog; Aristaless homeobox protein homolog; ARIX 1 homeodomain protein; ARIX; Arix homeodomain protein; ARIX1 homeodomain protein; CFEOM 2; CFEOM2; FEOM 2; FEOM2; Fibrosis of extraocular muscles congenital 2 autosomal recessive; MGC52227; NCAM 2; NCAM2; Paired like (aristaless) Homeobox 2A; Paired like homeobox 2a; Paired mesoderm homeobox 2a; Paired mesoderm homeobox protein 2A; Paired-like homeobox 2A; PHOX 2A; Phox2; Phox2a; PHX2A_HUMAN; Pmx 2a; Pmx2; Pmx2a.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PHOX2A (41-140aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]

Function:
May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype.

Subcellular Location:
Nucleus.xy-11172R    NAP1L2腦特異性蛋白BPX抗體
xy-11173R    NARF核纖層蛋白A識別因子抗體
xy-8334R    NIMPNOGO相互作用線粒體蛋白1抗體
xy-11099R    NLGN4X神經(jīng)元X連鎖蛋白/兒童自閉癥相關(guān)蛋白抗體
xy-11100R    NLGN4Y神經(jīng)元Y連鎖蛋白抗體（兒童自閉癥相關(guān)蛋白）
xy-11098R    NLGN2神經(jīng)連接蛋白2抗體
xy-11097R    NIPAL3NIPA樣蛋白3抗體
xy-11059R    NTN3軸突生長誘導(dǎo)因子3抗體
xy-11101R    NRXN3軸突蛋白3抗體
xy-6441R    NPD0141號染色體開放閱讀框63抗體
xy-12036R    NSG2神經(jīng)元特異性蛋白家族成員2抗體
xy-7877R    NEDD4神經(jīng)前體細胞發(fā)育下調(diào)蛋白4抗體
xy-8378R    NCE2泛素結(jié)合酶E2F抗體
xy-8090R    CCDC136鼻咽癌相關(guān)蛋白6抗體
xy-7871R    NEU4神經(jīng)氨酸酶4抗體
xy-7916R    N acetylglucosamine kinaseN-乙酰氨基葡萄糖激酶抗體
xy-11899R    NFIB核因子1B抗體
xy-11892R    NAV2維甲酸誘導(dǎo)神經(jīng)母細胞瘤蛋白1抗體
xy-11893R    NELF轉(zhuǎn)錄延伸因子NELF抗體
xy-11894R    NELL1蛋白激酶C結(jié)合蛋白NELL1抗體
xy-11895R    NELL2蛋白激酶C結(jié)合蛋白NELL2抗體
xy-11896R    NETO2腦特異性跨膜蛋白抗體
xy-11898R    NFIA核因子1A抗體
xy-11901R    NHLH1環(huán)一螺旋蛋白1抗體
xy-11902R    NME4腫瘤轉(zhuǎn)移抑制基因H4抗體
xy-11903R    神經(jīng)元衍生孤兒受體1抗體
xy-10065R    Netrin 4軸突生長誘向因子4抗體
xy-10029R    Nectin 4脊髓灰質(zhì)炎病毒受體相關(guān)蛋白4抗體
xy-10037R    NFKB p52細胞核因子/k基因結(jié)合核因子 p52/p100抗體
xy-11734R    NDUFS7線粒體復(fù)合物NDUFS7蛋白抗體