原鈣粘蛋白γA11抗體 返回列表頁

原鈣粘蛋白γA11抗體

英文名稱 PCDHGA11
中文名稱 原鈣粘蛋白γA11抗體
別    名 PCDH gamma A11; Protocadherin gamma A11; PCDGB_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  結(jié)合蛋白  細(xì)胞骨架  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHGA11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA11 (Protocadherin gamma-A11) is a 935 amino acid that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA11 is a member of the gamma subfamily A. PCDHGA11 is a type I transmembrane receptor containing six cadherin motifs and is expressed in the central nervous system where it localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGA11 that are produced as a result of alternative splicing events.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.xy-11502R    NENF神經(jīng)源性神經(jīng)營(yíng)養(yǎng)因子抗體
xy-11533R    Proprotein Convertase 2神經(jīng)內(nèi)分泌轉(zhuǎn)化酶2抗體
xy-11531R    NPW/Neuropeptide W神經(jīng)肽W抗體
xy-11521R    NPY5R神經(jīng)肽Y受體5抗體
xy-11522R    NPY4R神經(jīng)肽Y受體4抗體
xy-11523R    NHLH1 + NHLH2螺旋環(huán)螺旋蛋白1+2抗體
xy-11519R    Neuronatin胚胎神經(jīng)細(xì)胞NNAT抗體
xy-13766R    NUDCD3NUDCD3蛋白抗體
xy-13776R    NKR2B4CD244自然殺傷細(xì)胞受體2B4抗體
xy-2669R    phospho-NFATc2(Ser326)磷酸化核因子活化T細(xì)胞胞漿蛋白2抗體
xy-0353R    Nonylphenol壬基酚抗體
xy-11325R    Nova2神經(jīng)腫瘤Nova2抗原抗體
xy-3571R    NCOA3類固醇受體激活蛋白3抗體
xy-1858R    Netrin 1軸突導(dǎo)向因子1抗體
xy-0288R    TrkB酪氨酸激酶B抗體
xy-1812R    Notch3跨膜受體蛋白Notch-3抗體
xy-6982R    Neutrophil Elastase中性粒細(xì)胞彈性蛋白酶ELANE抗體
xy-4858R    Hepatitis C Virus RNA-directed RNA polymerase丙型肝炎病毒NS4B（65kDa）抗體
xy-7671R    NGFRAP1神經(jīng)生長(zhǎng)因子受體相關(guān)蛋白1抗體
xy-7672R    NRH2死亡結(jié)構(gòu)域蛋白NRH2抗體
xy-0046R    Neuronal thread protein AD7c-NTP神經(jīng)絲蛋白抗體
xy-0982R    phospho-NFKB p65(Ser536)磷酸化細(xì)胞核因子抗體
xy-1335R    Notch1跨膜受體蛋白Notch-1抗體
xy-3386R    Phospho-NR1D1(Ser55 + Ser59)磷酸化細(xì)胞核受體Rev-Erbα抗體
xy-10044R    Newcastle disease virus雞新城疫病毒抗體
xy-1537R    NADPH還原型輔酶Ⅱ/磷酸酰胺腺嘌呤二核苷酸抗體
xy-2012R    NIT2NIT2蛋白抗體
xy-1517R    NeuroD1神經(jīng)細(xì)胞分化因子1抗體
xy-1417R    NFAT2活化T細(xì)胞核因子1蛋白抗體
xy-2175R    NMDAR1谷氨酸受體1抗體
xy-2590R    NRSF/REST神經(jīng)元抑制蛋白抗體
xy-2304R    ARHGAP17神經(jīng)細(xì)胞發(fā)育相關(guān)調(diào)控蛋白抗體