原鈣粘蛋白β12抗體 返回列表頁

原鈣粘蛋白β12抗體

英文名稱 PCDHB12
中文名稱 原鈣粘蛋白β12抗體
別    名 PCDH beta12; PCDHB 12; PCDHB12; PCDBC_HUMAN.
  
說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  細(xì)胞骨架  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHB12
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. 

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.xy-4280R    Nck betaNCK銜接蛋白2抗體
xy-6597R    NPHS2腎小球裂孔膜蛋白PDCN抗體
xy-6563R    NMT1豆蔻?；D(zhuǎn)移酶1抗體
xy-7517R    Natriuretic Peptide Receptor A利鈉肽受體A抗體
xy-6235R    NRG3神經(jīng)調(diào)節(jié)蛋白3抗體
xy-7813R    NEDD1神經(jīng)前體細(xì)胞表達(dá)蛋白1抗體
xy-7814R    NEK1絲氨酸/蘇氨酸蛋白激酶NEK1抗體
xy-11593R    NAT8LN-乙酰轉(zhuǎn)移酶8樣蛋白抗體
xy-11443R    NMS神經(jīng)調(diào)節(jié)肽S抗體
xy-11444R    Nocturnin分子生物鐘調(diào)控蛋白NOC抗體
xy-11465R    Neogenin神經(jīng)細(xì)胞粘附蛋白NGN抗體
xy-11467R    Neuron navigator 1神經(jīng)細(xì)胞蛋白Nav1抗體
xy-11468R    Nogo B receptor軸索過度生長抑制因子B受體抗體
xy-4311R    NR0B2核受體0相關(guān)蛋白B家族2抗體
xy-6125R    phospho-p95 NBS1 (Ser343)磷酸化DNA修復(fù)蛋白NBS1抗體
xy-4753R    ASP4天冬氨酸蛋白酶ASP4抗體
xy-6233R    NMT2肉豆蔻?；D(zhuǎn)移酶2-N端肽抗體
xy-4246R    NFAT1核因子活化T細(xì)胞胞漿蛋白2抗體
xy-4212R    Neuroligin 1突觸細(xì)胞粘附分子1抗體
xy-2935R    Nucleoporin p62核孔糖蛋白P62抗體
xy-4724R    NT-3神經(jīng)營養(yǎng)因子3抗體
xy-8204R    NEEP21NEEP21蛋白抗體
xy-5382R    Phospho-NMDAR2B (Ser1480)磷酸化谷氨酸受體2B抗體
xy-5383R    Phospho-NMDAR2B (Ser1303)磷酸化谷氨酸受體2B抗體
xy-3957R    NDUFA10NADH氧化還原酶輔酶10抗體
xy-6204R    NCKAP1膜相關(guān)的蛋白質(zhì)HEM2抗體
xy-2378R    Notch 2跨膜受體蛋白Notch-2抗體
xy-3191R    Phospho-IKB beta (Ser23) 磷酸化KB抑制蛋白β抗體
xy-5509R    Phospho-NFKB1 (Ser903)磷酸化細(xì)胞核因子p50/k基因結(jié)合核因子抗體
xy-3812R    NEDD8泛素樣蛋白NEDD8抗體
xy-8171R    NFIC核因子1C型抗體
xy-5527R    phospho-NPTX1(Tyr344)磷酸化神經(jīng)細(xì)胞正五聚體1抗體
xy-8857R    RNA結(jié)合蛋白抗體
xy-8535R    phospho-NFATC4 (Ser168 + Ser170)磷酸化T細(xì)胞激活核轉(zhuǎn)錄因子4抗體