外周蛋白2抗體 返回列表頁

外周蛋白2抗體

英文名稱 PRPH2
中文名稱 外周蛋白2抗體
別    名 Peripherin-2; PRPH2; PRPH2_HUMAN; Retinal degeneration slow protein; Tetraspanin-22; Tspan-22.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細胞骨架  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRPH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.

Function:
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. 

Subunit:
Homodimer; disulfide-linked. Probably forms a complex with a ROM1 homodimer. Other proteins could associate with this complex in rods. Interacts with MREG. 

Subcellular Location:
Membrane; Multi-pass membrane protein. 

Tissue Specificity:
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.

DISEASE:
Defects in PRPH2 are the cause of retinitis pigmentosa type 7 (RP7). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.xy-13728R    PCDHGA6原鈣粘蛋白γA6抗體
xy-11116R    PCDHA2原鈣粘附蛋白α2抗體
xy-6712R    PAX4配對盒同源基因4抗體
xy-13711R    PR3白細胞蛋白酶3抗體
xy-13707R    PRELPPRELP蛋白抗體
xy-13723R    PCDH10原鈣粘附蛋白10抗體
xy-13724R    PCDHB1原鈣粘附蛋白β1抗體
xy-13725R    PCDHB10原鈣粘附蛋白β10抗體
xy-13726R    PCDHB6原鈣粘附蛋白β6抗體
xy-13727R    PCDHB14原鈣粘附蛋白β14抗體
xy-13729R    PCLKC鈣粘蛋白LKC抗體
xy-13730R    PLEKHA7PLEKHA7蛋白抗體
xy-13731R    PCDH21鈣粘蛋白21抗體
xy-13732R    PCDHB12鈣粘蛋白β12抗體
xy-10533R    phospho-PI3-kinase regulatory subunit gamma (Tyr199)磷酸化磷脂酰肌醇激酶調(diào)節(jié)亞單位gamma抗體
xy-1107R    PTHLH甲狀旁腺激素相關(guān)蛋白抗體
xy-0182R    PTP1B蛋白酪氨酸磷酸酶-1B抗體
xy-9188R    PROCA1Cyclin A1相互作用蛋白抗體
xym-0957M    PAG608 (3E4)野生型P53誘導(dǎo)基因1單克隆抗體
xy-2157R    Polycystin 1多囊腎蛋白1抗體
xy-2158R    Polycystin 2多囊腎蛋白2抗體
xy-1608R    PDCD4凋亡相關(guān)蛋白4抗體
xy-3593R    PI3 Kinase p110 delta磷脂酰肌醇激酶催化亞單位D抗體
xy-6081R    PDGFRL血小板源性生長因子受體β樣蛋白抗體
xy-3341R    Phospho-PLC beta3 (Ser1105)磷酸化磷酯酶Cβ3抗體
xy-3330R    Phospho-PERK(Thr980)磷酸化蛋白激酶樣內(nèi)質(zhì)網(wǎng)激酶抗體
xy-3528R    PFK26磷酸果糖激酶2抗體
xy-3331R    Phospho-PFK2 (Ser467)磷酸化6磷酸果糖激酶2抗體
xy-3332R    phospho-PI3 kinase p85 alpha + gamma (Tyr467 + Tyr199)磷酸化磷脂酰肌醇激酶抗體
xy-3333R    Phospho-PKC alpha/beta II (Thr638/641)磷酸化蛋白激酶C α/β2抗體
xy-3531R    PKC alpha蛋白激酶C α抗體
xy-3334R    Phospho-PKM2 (Tyr105)磷酸化丙酮酸激酶M2抗體
xy-3335R    Phospho-PKR (Thr446)磷酸化蛋白激酶R抗體
xy-3336R    Phospho-PKR (Thr451)磷酸化蛋白激酶R抗體