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含脯氨酸突觸相關蛋白相互作用蛋白1抗體

英文名稱 ProSAPiP1
中文名稱 含脯氨酸突觸相關蛋白相互作用蛋白1抗體
別    名 KIAA0552; PRIP1_HUMAN; Proline rich synapse associated protein interacting protein 1; ProSAP-interacting protein 1; ProSAPiP1; ProSAPiP1 protein.
 
說 明 書 0.1ml  0.2ml  
研究領域 神經(jīng)生物學  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ProSAPiP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The ProSAP family of proteins contain many protein-protein interaction domains and serve as scaffolding mediators within the post-synaptic density (PSD) of excitatory brain synapses. The PSD is an electron-dense structure underneath the post-synaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the pre-synaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). ProSAPiP1 (proline rich synapse associated protein interacting protein 1) is a 673 amino acid protein that interacts with the PDZ domain of Shank 3. ProSAPiP1 expression is brain-specific with highest expression within the cerebellum, hippocampus and cerebral cortex.

Subunit:
Interacts (via C-terminus) with SHANK3 (via PDZ domain). Interacts (via coiled coil) with SIPA1L1. Can form homooligomers (By similarity). xy-3337R    Phospho-PKR (Thr446 + Thr451)磷酸化蛋白激酶R抗體
xy-3338R    Phospho-PLCG2(Tyr1217)磷酸化磷酯酶Cγ2抗體
xy-3339R    Phospho-PLC gamma 2 (Tyr759)磷酸化磷酯酶Cγ2抗體
xy-3533R    PLCG 1磷酯酶Cγ1抗體
xy-3320R    Phospho-PDGFRA(Tyr849)/PDGFRB(Tyr857)磷酸化血小板源性生長因子受體α/β抗體
xy-3321R    Phospho-PDGF Receptor beta (Tyr1009)磷酸化血小板源性生長因子受體-B抗體
xy-3322R    Phospho-PDGF Receptor beta (Tyr1021)磷酸化血小板源性生長因子受體-B抗體
xy-3323R    Phospho-PDGF Receptor beta (Tyr740)磷酸化血小板源性生長因子受體-B抗體
xy-3324R    Phospho-PDGF Receptor beta (Tyr751)磷酸化血小板源性生長因子受體-B抗體
xy-3303R    Phospho-PDGF Receptor beta (Tyr771)磷酸化血小板源性生長因子受體-B抗體
xy-3325R    Phospho-PAR4 (Thr163)磷酸化蛋白酶活化受體4抗體
xy-3523R    PBKPDZ連接激酶/T-LAK細胞源蛋白激酶抗體
xy-3326R    Phospho-PBK (Thr9)磷酸化PDZ連接激酶/T-LAK細胞源蛋白激酶抗體
xy-3327R    Phospho-PDK1(Ser241)磷酸化3磷酸肌醇依賴性蛋白激酶1
xy-3524R    PEA15星形膠質細胞PEA15抗體
xy-6084R    POU6F2轉錄因子RPF1抗體
xy-6083R    PHAP1蛋白磷酸酶2A抑制劑1抗體
xy-6086R    Pinin橋粒相關蛋白DRS抗體
xy-0376R    PDSS2抑癌蛋白DLP1抗體
xy-6085R    PRKCDBP蛋白激酶C delta結合蛋白抗體
xy-2197R    duck hepatitis A virus polyprotein鴨甲型肝炎病毒聚蛋白抗體
xy-2639R    PGE2前列腺素E2抗體
xy-2444R    Pleiotrophin多效生長因子抗體
xy-5920R    PATZ1轉錄調節(jié)因子MAZR抗體
xy-6833R    PDCD6凋亡相關蛋白6抗體
xy-12142R    PATJPSD95相關緊密連接蛋白PATJ抗體
xy-12157R    PDGFAA + PDGFBB血小板源性生長因子AA+BB抗體
xy-6316R    PTGER1前列腺素EP1受體抗體
xy-1871R    P4HTM脯氨酸水解酶4抗體
xy-6769R    PHAPI2酸性核磷蛋白32家族B抗體
xy-7666R    PDCD2L程序性細胞死亡2樣抗體
xy-4507R    PRRSV M protein豬藍耳病病毒M蛋白抗體
xy-9352R    Proteasome 20S alpha 3蛋白酶體PSMα3抗體